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[5%或20%葡萄糖溶液输注对奶牛血糖和无机磷浓度的影响]

[Influence of an infusion of 5- or 20% glucose solution on blood glucose and inorganic phosphate concentrations in dairy cows].

作者信息

Aldaek T A A, Failing K, Wehrend A, Klymiuk M C

机构信息

Klinikum Veterinärmedizin, Klinik für Geburtshilfe, Gynäkologie und Andrologie, der Groß- und Kleintiere mit Tierärztlicher Ambulanz, Justus-Liebig-Universität Gießen, Frankfurter Straße 106, 35392 Gießen.

出版信息

Tierarztl Prax Ausg G Grosstiere Nutztiere. 2011;39(3):143-7.

PMID:22138798
Abstract

OBJECTIVE

The study was performed to evaluate the influence of an intravenous infusion of 5% and 20% dextrose solution on the plasma concentration of glucose and inorganic phosphate in healthy, dairy cows.

MATERIAL AND METHODS

Ten healthy, lactating, nonpregnant 3 to 6 year-old Holstein-Friesian cows were included in this investigation. The daily milk yield was 20.3±2.7 liters. Blood plasma concentrations of inorganic phosphate and glucose were determined before, during, immediately and 60 minutes after infusion of 0.9% physiological saline, 5% or 20% dextrose solution.

RESULTS

A statistically significant influence of dextrose infusion on blood glucose concentration was observed. After 20% dextrose infusion (200 g dextrose) the blood glucose concentration increased by approximately 13.26 mmol/l. The administration of 5% dextrose solution (50 g dextrose) yielded an increase of blood glucose concentration by 3.31 mmol/l. There was no significant correlation between plasma inorganic phosphate concentrations and infusion of 0.9% saline, 5% or 20% dextrose solution.

CONCLUSION AND CLINICAL RELEVANCE

Intravenous administration of 1000 ml of 5% or 20% dextrose solution does not induce a lasting plasma phosphate reduction and is suitable for elevating the blood glucose concentration.

摘要

目的

本研究旨在评估静脉输注5%和20%葡萄糖溶液对健康奶牛血浆葡萄糖和无机磷酸盐浓度的影响。

材料与方法

本研究纳入了10头健康、泌乳、未怀孕的3至6岁荷斯坦-弗里生奶牛。日均产奶量为20.3±2.7升。在输注0.9%生理盐水、5%或20%葡萄糖溶液之前、期间、输注后即刻和60分钟后,测定血浆无机磷酸盐和葡萄糖浓度。

结果

观察到葡萄糖输注对血糖浓度有统计学显著影响。输注20%葡萄糖溶液(200克葡萄糖)后,血糖浓度升高约13.26毫摩尔/升。输注5%葡萄糖溶液(50克葡萄糖)使血糖浓度升高3.31毫摩尔/升。血浆无机磷酸盐浓度与输注0.9%生理盐水、5%或20%葡萄糖溶液之间无显著相关性。

结论及临床意义

静脉输注1000毫升5%或20%葡萄糖溶液不会导致血浆磷酸盐持续降低,适用于提高血糖浓度。

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