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血液透析患者的血管通路类型、健康相关生活质量与抑郁:初步报告

Vascular access type, health-related quality of life, and depression in hemodialysis patients: a preliminary report.

作者信息

Afsar Baris, Elsurer Rengin, Covic Adrian, Kanbay Mehmet

机构信息

Department of Nephrology, Zonguldak Atatürk Government Hospital, Zonguldak, Turkey.

出版信息

J Vasc Access. 2012 Apr-Jun;13(2):215-20. doi: 10.5301/jva.5000032.

Abstract

PURPOSE

Arteriovenous fistulas (AVF) are the vascular access of choice for hemodialysis (HD) compared with arteriovenous grafts (AVG) and central venous catheters (CVC). In spite of increasing recognition of importance of a patient's perception of health-related quality of life (HRQOL) and depression, few studies have assessed the association of vascular access type with HRQOL and depression. The purpose of our study was to examine HRQOL and depression among patients with different vascular access.

METHODS

Severity of symptoms of depression and HRQOL were assessed by Beck Depression Inventory (BDI) and Short Form-36 (SF-36), respectively. Vascular access was reported as one of three options; AVF, AVG, and CVC.

RESULTS

In total, 136 patients were included; 104 had AVF, 15 had AVG, and 17 had CVC. BDI and HRQOL parameters differed among patients with different vascular access types. In post hoc analysis, BDI and HRQOL subscales were not different between patients with AVF and AVG. Patients with CVC had lower physical functioning (P:.001), role-physical limitation (P:.015), general health perception (P:.017), vitality (P:.010), social functioning (P:.004), role-emotional (P:.008), mental health (P:.001), physical component summary score (P:.017), and mental component summary score (P:.006) when compared to patients with AVF. Patients with CVC had lower physical functioning (P:.044), role-emotional (P:.044) and mental health scores (P:.04) when compared to patients with AVG.

CONCLUSIONS

Having a CVC may negatively influence HRQOL in HD patients. Vascular access type does not seem to be related to depressed mood in HD.

摘要

目的

与动静脉移植物(AVG)和中心静脉导管(CVC)相比,动静脉内瘘(AVF)是血液透析(HD)首选的血管通路。尽管人们越来越认识到患者对健康相关生活质量(HRQOL)的认知和抑郁的重要性,但很少有研究评估血管通路类型与HRQOL和抑郁之间的关联。我们研究的目的是检查不同血管通路患者的HRQOL和抑郁情况。

方法

分别通过贝克抑郁量表(BDI)和简明健康状况调查问卷(SF-36)评估抑郁症状的严重程度和HRQOL。血管通路报告为三种选择之一:AVF、AVG和CVC。

结果

总共纳入了136例患者;104例有AVF,15例有AVG,17例有CVC。不同血管通路类型的患者BDI和HRQOL参数不同。在事后分析中,AVF和AVG患者的BDI和HRQOL子量表没有差异。与AVF患者相比,CVC患者的身体功能(P = 0.001)、角色-身体限制(P = 0.015)、总体健康感知(P = 0.017)、活力(P = 0.010)、社会功能(P = 0.004)、角色-情感(P = 0.008)、心理健康(P = 0.001)、身体成分汇总得分(P = 0.017)和心理成分汇总得分(P = 0.006)较低。与AVG患者相比,CVC患者的身体功能(P = 0.044)、角色-情感(P = 0.044)和心理健康得分(P = 0.04)较低。

结论

使用CVC可能会对HD患者的HRQOL产生负面影响。血管通路类型似乎与HD患者的抑郁情绪无关。

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