Keser Betul Nur, Kirman Ulku Nur, Kocaaslan Cemal, Aydin Ebuzer
School of Medicine, Istanbul Medeniyet University, Goztepe Education and Research Hospital, Istanbul, Turkey.
Cardiovascular Surgery Department, Istanbul Medeniyet University, Goztepe Education and Research Hospital, Istanbul, Turkey.
Vascular. 2020 Aug;28(4):390-395. doi: 10.1177/1708538120905725. Epub 2020 Feb 20.
A well-functioning vascular access is crucial for hemodialysis treatment, and arteriovenous fistula is the recommended vascular access type. Arteriovenous fistula is superior to other vascular access types in many aspects, but the effect of arteriovenous fistula on patients' psychiatric state is not well described yet. The aim of this study is to determine whether there is an association between vascular access type and depression scores.
This cross-sectional study was conducted at two hemodialysis centers. Geriatric Depression Scale-15 was administered to geriatric hemodialysis patients, using ≥5 score as the cut-off value for the presence of depressive symptoms. Descriptive tests, Kolmogorov-Smirnov test, Pearson's Chi-square test, Mann-Whitney test, Kruskal-Wallis test, Spearman's rank correlation calculation, and multiple logistic regression analysis were performed accordingly to analyze the data.
Of 75 participants, 34 (45.3%) were female and the mean age was 73.4 ± 5.9 years (range: 65-92). The prevalence of depressive symptoms in the geriatric hemodialysis population was 53.3%. Central venous catheter, hypertension, and increased time on hemodialysis have been found to be risk factors for higher depression scores (aOR 10.505 (95% CI 1.435-76.900), = 0.021; aOR 9.783 (95% CI 2.508-38.169), = 0.001; aOR 1.019 (95% CI 1.003-1.035), = 0.017, respectively). Among patients with arteriovenous fistula, those with hypertension had higher depression scores ( = 0.008).
Geriatric hemodialysis patients were found to have depressive symptoms commonly, and central venous catheter, hypertension, and increased time on hemodialysis have been found to be risk factors for presence of depressive symptoms. To the best of our knowledge, this is the first study highlighting that arteriovenous fistula is associated with lower depression scores and lower prevalence of depressive symptoms.
功能良好的血管通路对于血液透析治疗至关重要,动静脉内瘘是推荐的血管通路类型。动静脉内瘘在许多方面优于其他血管通路类型,但动静脉内瘘对患者精神状态的影响尚未得到充分描述。本研究的目的是确定血管通路类型与抑郁评分之间是否存在关联。
这项横断面研究在两个血液透析中心进行。对老年血液透析患者进行老年抑郁量表-15评估,以≥5分作为存在抑郁症状的临界值。相应地进行描述性检验、柯尔莫哥洛夫-斯米尔诺夫检验、皮尔逊卡方检验、曼-惠特尼检验、克鲁斯卡尔-沃利斯检验、斯皮尔曼等级相关计算和多元逻辑回归分析来分析数据。
75名参与者中,34名(45.3%)为女性,平均年龄为73.4±5.9岁(范围:65 - 92岁)。老年血液透析人群中抑郁症状的患病率为53.3%。已发现中心静脉导管、高血压和血液透析时间延长是抑郁评分较高的危险因素(调整后比值比分别为10.505(95%置信区间1.435 - 76.900),P = 0.021;9.783(95%置信区间2.508 - 38.169),P = 0.001;1.019(95%置信区间1.003 - 1.035),P = 0.017)。在有动静脉内瘘的患者中,患有高血压的患者抑郁评分更高(P = 0.008)。
发现老年血液透析患者普遍存在抑郁症状,并且已发现中心静脉导管、高血压和血液透析时间延长是存在抑郁症状的危险因素。据我们所知,这是第一项强调动静脉内瘘与较低抑郁评分和较低抑郁症状患病率相关的研究。