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喉返神经损伤所致声带麻痹的组织病理学

Histopathology of vocal cord palsy from recurrent laryngeal nerve damage.

作者信息

Quiney R E, Michaels L

机构信息

Royal National Throat Nose and Ear Hospital, London, England.

出版信息

J Otolaryngol. 1990 Aug;19(4):237-41.

PMID:2213995
Abstract

The detailed postmortem laryngeal findings of a man with an established vocal cord palsy from an inoperable bronchial carcinoma is presented. Fine dissection of the monoblock specimen from skull base to superior mediastinum allowed sampling of vagus, recurrent and superior laryngeal nerves at different levels for fiber counts in order to compare the affected left and unaffected right side. Horizontal slicing of the whole larynx showed that the main cause of lateral displacement of the paralyzed left cord was gross atrophy of the underlying intrinsic laryngeal muscles. Cricothyroid muscle and superior laryngeal nerves were unaffected. Lateral cord drift due to underlying muscle atrophy is a better explanation of paralyzed cord position in this case than the Wagner and Grossmann theory of cord palsy.

摘要

本文呈现了一名患有无法手术切除的支气管癌且已确诊声带麻痹男性的详细尸检喉部结果。对从颅底到上纵隔的整块标本进行精细解剖,以便在不同水平采集迷走神经、喉返神经和喉上神经进行纤维计数,从而比较患侧左侧和未受影响的右侧。对整个喉部进行水平切片显示,左侧麻痹声带向外侧移位的主要原因是其下方喉内肌的严重萎缩。环甲肌和喉上神经未受影响。在这种情况下,相较于瓦格纳和格罗斯曼的声带麻痹理论,由下方肌肉萎缩导致的声带向外侧移位能更好地解释麻痹声带的位置。

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