单纯疱疹病毒在多发性硬化症患者、淋巴瘤患者及正常人中的潜伏情况。
Herpes simplex virus latency in patients with multiple sclerosis, lymphoma and normal humans.
作者信息
Warren K G, Devlin M, Gilden D H, Wroblewska Z, Koprowski H, Brown S M, Subak-Sharpe J
出版信息
IARC Sci Publ (1971). 1978(24 Pt 2):765-8.
PMID:221401
Abstract
Herpes simplex virus (HSV) was isolated from the trigeminal ganglia (TG) of 12 cadavers (10 traumatic deaths, one lymphoma and one multiple sclerosis). The cadaver with multiple sclerosis showed large bilateral trigeminal nerve root entry zone areas of demyelination. It is hypothesized that HSV is capable of migrating to the trigeminal nerve root entry zone and initiating demyelinating disease.
摘要
从12具尸体（10例外伤死亡、1例淋巴瘤和1例多发性硬化症患者）的三叉神经节（TG）中分离出单纯疱疹病毒（HSV）。患有多发性硬化症的尸体显示双侧三叉神经根进入区有大面积脱髓鞘。据推测，HSV能够迁移至三叉神经根进入区并引发脱髓鞘疾病。
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