Ikeda S, Manabe M, Ogawa H, Inaba Y
Department of Dermatology, Juntendo University, School of Medicine, Tokyo.
Nihon Hifuka Gakkai Zasshi. 1990 Jun;100(7):805-9.
Exact body height and weight data of patient with epidermolysis bullosa simplex (EBS) and recessive dystrophic epidermolysis bullosa (RDEB) were collected through a nation-wide epidemiologic investigation concerning epidermolysis bullosa (EB) patients. This data was then compared with the averaged body height and weight of age and sex matched normal controls. The nutritional condition of the EB patients was evaluated statistically. The data showed that height of female EBS patients was less than the controls (p less than 0.01), and furthermore, that height and weight of male and female RDEB patients was also less than the controls (p less than 0.01). These results indicated that EB, especially RDEB patients, were in the poor nutritional condition, and that the adequate nutritional management might significantly influence the prognosis of these patients.
通过一项关于大疱性表皮松解症(EB)患者的全国性流行病学调查,收集了单纯性大疱性表皮松解症(EBS)和隐性营养不良性大疱性表皮松解症(RDEB)患者的确切身高和体重数据。然后将这些数据与年龄和性别匹配的正常对照组的平均身高和体重进行比较。对EB患者的营养状况进行了统计学评估。数据显示,女性EBS患者的身高低于对照组(p<0.01),此外,男性和女性RDEB患者的身高和体重也低于对照组(p<0.01)。这些结果表明,EB患者,尤其是RDEB患者,营养状况较差,适当的营养管理可能会显著影响这些患者的预后。