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在 300MHz 下测量的面部皮肤介电常数的性别差异。

Gender differences in facial skin dielectric constant measured at 300 MHz.

机构信息

College of Medical Sciences, Nova Southeastern University, Ft. Lauderdale, Florida, USA.

出版信息

Skin Res Technol. 2012 Nov;18(4):504-10. doi: 10.1111/j.1600-0846.2011.00582.x. Epub 2011 Dec 5.

Abstract

BACKGROUND/PURPOSE: Skin tissue dielectric constant (TDC) measurements at 300 MHz provide non-invasive data on free and bound tissue water. TDC-data is available for some body sites, but most is for female forearm. Contrastingly, there are no data on face-skin or comparative data between genders. Our goals were to obtain facial-TDC reference values and determine if TDC-values differ between genders.

METHODS

TDC was measured at forehead, cheek, and forearm in 60 young adults (30 men) to a 1.5-mm depth. Measured TDC-values were compared with TDC-values calculated using skin-thickness data.

RESULTS

Measured TDC-values ranged from 39.6 ± 2.9 at male-forehead to 28.2 ± 2.4 at female forearm and were significantly different (P < 0.001) among each site in the order forehead > cheek >forearm. Male TDC-values were greater than female TDC-values (P < 0.01) with differences from 5.6% at forehead to 11.3% at forearm. Calculated TDC-values incorporating site and gender skin-thickness differences yielded TDC-values at the most 3% different from measured values.

CONCLUSION

Gender differences should be considered in clinical studies in which men and women are included in a common study population with respect to experimental design and data interpretation. This is especially true if absolute TDC-values are of interest rather than changes in TDC-values on the same subject subsequent secondary to an intervention.

摘要

背景/目的:300MHz 下的皮肤组织介电常数(TDC)测量可提供游离组织水和结合组织水的非侵入性数据。已有一些身体部位的 TDC 数据,但大多是女性前臂的。相比之下,面部皮肤的 TDC 数据却没有,不同性别之间也没有比较数据。我们的目标是获得面部皮肤 TDC 的参考值,并确定 TDC 值是否存在性别差异。

方法

在 60 名年轻成年人(30 名男性)的前额、脸颊和前臂处测量了 1.5mm 深度的 TDC。将实测 TDC 值与使用皮肤厚度数据计算得到的 TDC 值进行比较。

结果

实测 TDC 值范围从男性前额的 39.6 ± 2.9 到女性前臂的 28.2 ± 2.4,每个部位的 TDC 值均存在显著差异(P < 0.001),前额 > 脸颊 > 前臂。男性 TDC 值大于女性 TDC 值(P < 0.01),差异范围从 5.6%(前额)到 11.3%(前臂)。考虑到部位和性别皮肤厚度差异,计算得到的 TDC 值与实测值的差异最大不超过 3%。

结论

在涉及男性和女性的临床研究中,应考虑性别差异,包括实验设计和数据解释。如果关注的是绝对 TDC 值,而不是同一对象后续干预后 TDC 值的变化,则尤其如此。

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