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预测简单催化反应模型中基于模板的催化速率。

Predicting template-based catalysis rates in a simple catalytic reaction model.

机构信息

University of Lausanne, Department of Ecology and Evolution, Lausanne, Switzerland.

出版信息

J Theor Biol. 2012 Feb 21;295:132-8. doi: 10.1016/j.jtbi.2011.11.024. Epub 2011 Dec 2.

Abstract

We show that in a particular model of catalytic reaction systems, known as the binary polymer model, there is a mathematical concordance between two versions of the model: (1) random catalysis and (2) template-based catalysis. In particular, we derive an analytical calculation that allows us to accurately predict the (observed) required level of catalysis in one version of the model from that in the other version, for a given probability of having self-sustaining autocatalytic sets exist in instances of both model versions. This provides a tractable connection between two models that have been investigated in theoretical origin-of-life studies.

摘要

我们表明,在一种称为二元聚合物模型的特定催化反应系统模型中,该模型的两个版本(1)随机催化和(2)基于模板的催化之间存在数学一致性。具体来说,我们推导出一个分析计算,允许我们从另一个版本准确预测给定模型版本中自维持自催化集存在的概率下,一个版本中所需的(观察到的)催化水平。这为理论生命起源研究中研究的两个模型之间提供了一种可行的联系。

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