Leja Monika J, Kim Min, Perryman Lynda, Blackmon Shanda H, Reardon Michael J
Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Methodist Debakey Cardiovasc J. 2011 Oct-Dec;7(4):44-6. doi: 10.14797/mdcj-7-4-44.
Melanoma has a known propensity for cardiac metastasis. Most cases are associated with widespread metastatic disease and multiple sites of cardiac involvement and are not appropriate for surgical resection. When there is an isolated metastasis to the heart, the melanoma tends to involve the right heart. Rarely does melanoma metastasize only to the left ventricle. We present an unusual case of isolated metastasis of melanoma to the intracavitary left ventricle. This tumor was poorly responsive to chemotherapy, and a cardiac autotransplantation technique was used to achieve complete resection with pathologically negative margins.
黑色素瘤有向心脏转移的倾向。大多数病例与广泛的转移性疾病和心脏多部位受累有关,不适合手术切除。当心脏出现孤立性转移时,黑色素瘤往往累及右心。黑色素瘤很少仅转移至左心室。我们报告一例罕见的黑色素瘤孤立性转移至左心腔内的病例。该肿瘤对化疗反应不佳,采用心脏自体移植技术实现了切缘病理阴性的完整切除。