Department of Radiology, University of Virginia, 1218 Lee St, Box 800170, Charlottesville, VA 22908, USA.
Radiology. 2012 Feb;262(2):576-83. doi: 10.1148/radiol.11111225. Epub 2011 Dec 5.
To prospectively determine whether the addition of an intraarticular anesthetic to the magnetic resonance (MR) arthrography solution has an effect on periprocedural pain, motion artifacts, and imaging time.
This study was approved by the institutional review board, and written informed consent was obtained from all patients. From September 2009 to March 2010, 127 patients, most imaged for shoulder pain, were randomized into two groups. The first group (group A, 63 patients) received intraarticular injection of gadopentetate dimeglumine, ropivacaine 0.5%, and normal saline in a ratio of 1:100:100. The second group (group B, 64 patients) received intraarticular injection of gadopentetate dimeglumine and normal saline in a ratio of 1:200. Pain was assessed before and after injection and immediately after 1.5-T MR imaging and rated on a scale of 0 to 10. Motion artifact was assessed by two musculoskeletal radiologists and two fellows by using a scale of 0 to 3 (0=no artifact, 1=artifact present but not affecting diagnostic image quality, 2=artifact present and diminishing diagnostic image quality, and 3=artifact present and rendering image nondiagnostic). MR imaging time and examinations with repeated sequences were recorded. Wilcoxon rank sum, analysis of covariance, and permutation data analyses were performed.
The mean pain levels before injection, after injection, and after MR imaging were 3.5, 2.3, and 2.5, respectively, for group A and 3.6, 3.1, and 3.2 for group B. After adjusting for age, sex, and preinjection pain level, the mean differences in pre- and postinjection pain and preinjection pain and post-MR imaging pain between the two groups were -0.9 (P=.017) and -0.8 (P=.056), respectively. No significant difference in mean total MR imaging time or number of patients with repeat sequences was noted. Radiologists 1 and 2 recorded grade 2 or 3 motion in six and five patients, respectively, in group A and 15 and 14 patients, respectively, in group B (P=.047 and .048, respectively). Radiologists 3 and 4 recorded grade 2 or 3 motion in 13 and 23 patients, respectively, in group A and 23 and 33 patients, respectively, in group B (P=.093 and .110, respectively).
The use of an intraarticular anesthetic significantly reduces periprocedural pain and major motion artifacts associated with MR shoulder arthrography; however, total MR imaging time is not reduced.
前瞻性确定关节内麻醉是否会影响磁共振(MR)关节造影术的围手术期疼痛、运动伪影和成像时间。
本研究经机构审查委员会批准,并获得所有患者的书面知情同意。2009 年 9 月至 2010 年 3 月,127 例(主要因肩部疼痛进行成像)患者随机分为两组。第一组(A 组,63 例)接受关节内注射钆喷替酸二葡甲胺、罗哌卡因 0.5%和生理盐水,比例为 1:100:100。第二组(B 组,64 例)接受关节内注射钆喷替酸二葡甲胺和生理盐水,比例为 1:200。注射前后及 1.5-T MR 成像后立即评估疼痛,并按 0 到 10 分的等级进行评分。两名肌肉骨骼放射科医生和两名研究员使用 0 到 3 分的量表评估运动伪影(0=无伪影,1=存在伪影但不影响诊断图像质量,2=存在伪影且降低诊断图像质量,3=存在伪影且使图像不可诊断)。记录磁共振成像时间和重复序列检查。采用 Wilcoxon 秩和检验、协方差分析和置换数据分析。
A 组注射前、注射后和注射后磁共振成像的平均疼痛水平分别为 3.5、2.3 和 2.5,B 组分别为 3.6、3.1 和 3.2。调整年龄、性别和注射前疼痛水平后,两组间注射前后疼痛和注射前疼痛与注射后磁共振成像疼痛的平均差异分别为-0.9(P=.017)和-0.8(P=.056)。两组平均总磁共振成像时间或有重复序列的患者数量无显著差异。放射科医生 1 和 2 分别在 A 组的 6 名和 5 名患者、B 组的 15 名和 14 名患者中记录了 2 级或 3 级运动(P=.047 和.048)。放射科医生 3 和 4 分别在 A 组的 13 名和 23 名患者、B 组的 23 名和 33 名患者中记录了 2 级或 3 级运动(P=.093 和.110)。
关节内麻醉的使用可显著减轻与磁共振肩关节造影术相关的围手术期疼痛和主要运动伪影;然而,磁共振成像总时间并未减少。