van Helden Jacques, Toussaint Ariane, Thieffry Denis
Laboratoire de Bioinformatique des Génomes et des Réseaux, Université Libre de Bruxelles, Bruxelles, Belgium.
Methods Mol Biol. 2012;804:1-11. doi: 10.1007/978-1-61779-361-5_1.
This introductory review synthesizes the contents of the volume Bacterial Molecular Networks of the series Methods in Molecular Biology. This volume gathers 9 reviews and 16 method chapters describing computational protocols for the analysis of metabolic pathways, protein interaction networks, and regulatory networks. Each protocol is documented by concrete case studies dedicated to model bacteria or interacting populations. Altogether, the chapters provide a representative overview of state-of-the-art methods for data integration and retrieval, network visualization, graph analysis, and dynamical modelling.
这篇引言性综述综合了《分子生物学方法》系列丛书中《细菌分子网络》卷的内容。该卷汇集了9篇综述和16个方法章节，描述了用于分析代谢途径、蛋白质相互作用网络和调控网络的计算协议。每个协议都有专门针对模式细菌或相互作用群体的具体案例研究作为记录。总之，这些章节提供了数据整合与检索、网络可视化、图分析和动态建模等最新方法的代表性概述。
