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[引发2009年大流行的甲型流感病毒(H1N1)毒株的遗传学特征]

[Genetical features of influenza virus A (H1N1) strain that caused the 2009 pandemic].

作者信息

Susloparov I M, Sharshov K A, Romanovskaia A A, Durymanov A G, Alekseev A Iu, Stavskiĭ E A, Malkova E M, Shestopalov A M

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 2011 Sep-Oct(5):107-10.

Abstract

Genetical features of the A(H1N1) influenza virus strain that caused the 2009 pandemic are analyzed in the review. Mutations typical for this strain, unique and similar to influenza viruses of swine, avian and seasonal types, and phenotypic (pathologic) features associated with them, that are experimentally confirmed, are described. A possibility of reassortation of avian and swine influenza viruses and possible epidemiologic consequences are discussed.

摘要

该综述分析了引发2009年大流行的甲型(H1N1)流感病毒株的遗传特征。描述了该病毒株特有的、与猪、禽和季节性流感病毒相似的独特突变,以及与之相关的经实验证实的表型(病理)特征。讨论了禽源和猪源流感病毒重配的可能性及其可能的流行病学后果。

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