Subbiah Sridhar, Palikhe Gaurav, Bhadada Sanjay Kumar, Mukherjee Kanchan Kumar, Bhansali Anil
Department of Endocrinology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
J Pediatr Endocrinol Metab. 2011;24(9-10):835-7. doi: 10.1515/jpem.2011.274.
McCune-Albright syndrome (MAS) is characterized by a triad of poly/monoostotic fibrous dysplasia, café-au-lait macules and hyperfunctioning endocrinopathies. Association of MAS with GH excess is rare, and in most of the instances somatotropinoma has not been documented. Treatment of patients of MAS with acromegaly is difficult because of thickened calvarium and dysplastic skull bone. We report a 17-year-old girl, who presented with cranio-facial fibrous dysplasia, café-au-lait macules and also had acromegaly due to pituitary macroadenoma, and treated with gamma knife radiosurgery.
McCune-Albright综合征（MAS）的特征为多/单骨纤维性发育不良、咖啡斑和内分泌功能亢进三联征。MAS与生长激素过量相关的情况罕见，且在大多数病例中未记录到生长激素瘤。由于颅骨增厚和颅骨发育异常，治疗患有肢端肥大症的MAS患者很困难。我们报告一名17岁女孩，她患有颅面部纤维性发育不良、咖啡斑，还因垂体大腺瘤患有肢端肥大症，并接受了伽玛刀放射外科治疗。
