Vittala International Institute of Ophthalmology & Prabha Eye Clinic & Research Centre, Bangalore, India.
Retina. 2012 May;32(5):1017-20. doi: 10.1097/IAE.0b013e31822d3a20.
To look for clinical parameters that will assist in making a diagnosis of tubercular or sarcoid uveitis in a South Indian patient population
Retrospective, nonrandomized, comparative study of 51 patients with a diagnosis of biopsy-proven tuberculosis and sarcoidosis. These patients had a minimum of 1-year follow-up after initiating treatment for either disease. Multivariate logistic regression analysis was used to determine clinical predictors of tubercular uveitis.
The mean age group was 47.08 ± 11.19 years. There were 39 women and 12 men in the study. Multivariate logistic regression analysis shows likelihood of uveitis being tubercular in etiology using 3 variables: Schirmer test >10 mm, retinal vasculitis with areas of multiple, pigmented chorioretinal atrophy along blood vessels, and a positive Mantoux test 76.6%.
A combination of Schirmer test >10 mm, retinal vasculitis with areas of multiple, pigmented chorioretinal atrophy along blood vessels, and positive Mantoux test may be used clinically to differentiate tubercular from sarcoid uveitis in our patient population.
寻找有助于在印度南部患者人群中诊断结核性或结节病性葡萄膜炎的临床参数。
对 51 例经活检证实的结核和结节病患者进行回顾性、非随机、对照研究。这些患者在开始治疗任何一种疾病后至少有 1 年的随访。采用多变量逻辑回归分析确定结核性葡萄膜炎的临床预测因素。
平均年龄组为 47.08 ± 11.19 岁。研究中有 39 名女性和 12 名男性。多变量逻辑回归分析显示，使用 3 个变量（Schirmer 试验> 10mm、视网膜血管炎伴血管旁多发性色素性脉络膜视网膜萎缩、曼托试验阳性），葡萄膜炎病因结核的可能性为 76.6%。
在我们的患者人群中，Schirmer 试验> 10mm、视网膜血管炎伴血管旁多发性色素性脉络膜视网膜萎缩、曼托试验阳性的组合可用于临床区分结核性和结节病性葡萄膜炎。
