一例伴有肾母细胞瘤成分的腹膜后未成熟畸胎瘤。

A case of retroperitoneal immature teratoma with nephroblastic components.

作者信息

Ishida Mitsuaki, Hotta Machiko, Ohta Motoki, Taga Takashi, Ohta Shigeru, Takeuchi Yoshihiro, Okabe Hidetoshi

机构信息

Department of Clinical Laboratory Medicine, Division of Diagnostic Pathology. Shiga University of Medical Science, Shiga, Japan.

出版信息

J Pediatr Hematol Oncol. 2012 Jan;34(1):e22-5. doi: 10.1097/MPH.0b013e31822ea010.

DOI:10.1097/MPH.0b013e31822ea010

PMID:22146529

Abstract

The presence of nephroblastic components is extremely rare in retroperitoneal teratomas. We described an unusual case of right retroperitoneal immature teratoma with nephroblastic components in a 2-month-old Japanese girl. Approximately 15% of tumor was composed of nephroblastic components within immature teratoma components. Although overlap of histopathological findings between teratomas with nephroblastic components and teratoid Wilms tumors, which have heterologous elements in >50% of the tumor, occasionally exist, the most distinct feature of teratoma is the presence of organoid arrangement. The prognosis of retroperitoneal teratomas with nephroblastic components has not yet been established, therefore, additional case studies are needed.

摘要

肾母细胞瘤成分在腹膜后畸胎瘤中极为罕见。我们描述了一名2个月大的日本女孩，患有一例罕见的右侧腹膜后未成熟畸胎瘤并伴有肾母细胞瘤成分。在未成熟畸胎瘤成分中，约15%的肿瘤由肾母细胞瘤成分构成。尽管具有肾母细胞瘤成分的畸胎瘤与畸胎样肾母细胞瘤（肿瘤中>50%具有异源性成分）的组织病理学表现偶尔会有重叠，但畸胎瘤最显著的特征是存在类器官排列。伴有肾母细胞瘤成分的腹膜后畸胎瘤的预后尚未明确，因此，需要更多的病例研究。