针灸治疗化疗引起的周围神经病变（CIPN）：一项使用神经影像学的初步研究。
Acupuncture for chemotherapy-induced peripheral neuropathy (CIPN): a pilot study using neurography.
机构信息
HanseMerkur Centre for TCM at the University Medical Center, UKE-Campus, House O55, Martinistrasse 52, 20246, Hamburg, Germany.
出版信息
Acupunct Med. 2012 Mar;30(1):4-7. doi: 10.1136/acupmed-2011-010034. Epub 2011 Dec 5.
OBJECTIVES
Chemotherapy-induced peripheral neuropathy (CIPN) can produce severe neurological deficits and neuropathic pain and is a potential reason for terminating or suspending chemotherapy treatments. Specific and effective curative treatments are lacking.
METHODS
A pilot study was conducted to evaluate the therapeutic effect of acupuncture on CIPN as measured by changes in nerve conduction studies (NCS) in six patients treated with acupuncture for 10 weeks in addition to best medical care and five control patients who received the best medical care but no specific treatment for CIPN.
RESULTS
In five of the six patients treated with acupuncture, NCS improved after treatment. In the control group, three of five patients did not show any difference in NCS, one patient improved and one showed impaired NCS.
CONCLUSION
The data suggest that acupuncture has a positive effect on CIPN. The encouraging results of this pilot study justify a randomised controlled trial of acupuncture in CIPN on the basis of NCS.
目的
化疗引起的周围神经病（CIPN）可导致严重的神经功能缺损和神经病理性疼痛，是终止或暂停化疗治疗的潜在原因。目前缺乏特异性和有效的治疗方法。
方法
进行了一项试点研究，以评估针刺治疗 CIPN 的疗效，该研究纳入了 6 例接受针刺治疗 10 周的患者和 5 例接受最佳药物治疗但未接受 CIPN 特异性治疗的患者，通过神经传导研究（NCS）的变化来评估。
结果
在接受针刺治疗的 6 例患者中，有 5 例的 NCS 在治疗后得到改善。在对照组中，5 例患者中有 3 例 NCS 无差异，1 例改善，1 例恶化。
结论
数据表明针刺对 CIPN 有积极影响。这项试点研究的令人鼓舞的结果证明了基于 NCS 的针刺治疗 CIPN 的随机对照试验是合理的。
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