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无缝线羊膜移植联合窄条自体结膜移植治疗翼状胬肉

Sutureless amniotic membrane transplantation combined with narrow-strip conjunctival autograft for pterygium.

作者信息

Taylan Sekeroglu Hande, Erdem Elif, Dogan Nese Cetin, Yagmur Meltem, Ersoz Reha, Dogan Ahmet

机构信息

Department of Ophthalmology, Cukurova University, Balcali Hospital, 01130, Yuregir, Adana, Turkey.

出版信息

Int Ophthalmol. 2011 Dec;31(6):433-8. doi: 10.1007/s10792-011-9488-y. Epub 2011 Dec 7.

Abstract

To study the efficacy and safety of sutureless amniotic membrane transplantation combined with narrow-strip conjunctival autograft and to investigate the clinical outcomes. Thirty eyes of 30 patients with primary pterygia were treated in this institutional study with excision followed by sutureless amniotic membrane transplantation combined with narrow-strip conjunctival autograft using fibrin glue tissue adhesive. The main outcome measures were the operating time for ocular surface reconstruction, the size of the pterygium and of the conjunctival autograft, postoperative complications, subjective complaints, and recurrences. The mean pterygium size was 3.12 ± 0.92 mm and the mean operating time was 4.58 ± 1.10 min. Twenty-nine patients (96.7%) had no complaints after first postoperative week. Twenty-eight (93.3%) patients had no recurrences after 1 year follow-up. The sutureless amniotic membrane transplantation combined with narrow-strip conjunctival autograft is an effective procedure with low rate of recurrence. This technique can be considered as a preferred grafting procedure for primary pterygium but further randomized controlled studies including larger populations are needed.

摘要

研究无缝合羊膜移植联合窄条自体结膜移植的疗效和安全性,并探讨其临床效果。在本机构研究中,对30例原发性翼状胬肉患者的30只眼进行治疗,先切除翼状胬肉,然后使用纤维蛋白胶组织粘合剂进行无缝合羊膜移植联合窄条自体结膜移植。主要观察指标包括眼表重建手术时间、翼状胬肉和自体结膜移植片的大小、术后并发症、主观症状及复发情况。翼状胬肉平均大小为3.12±0.92mm,平均手术时间为4.58±1.10分钟。29例患者(96.7%)术后第一周后无不适主诉。28例患者(93.3%)随访1年后无复发。无缝合羊膜移植联合窄条自体结膜移植是一种有效的手术方法,复发率低。该技术可被视为原发性翼状胬肉的首选移植手术,但需要进一步开展包括更大样本量的随机对照研究。

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