Alpay Atilla, Uğurbaş Suat Hayri, Erdoğan Berktuğ
Department of Ophthalmology, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey.
Clin Ophthalmol. 2009;3:69-74. Epub 2009 Jun 2.
To compare various techniques of pterygium surgery including bare sclera, intraoperative mitomycin C application, conjunctival flap reconstruction, and conjunctival autografting technique.
This study is designed to compare 4 currently used techniques in order to determine the complication and recurrence rates after pterygium exision. Included in the study were 77 eyes from 60 patients. Bare sclera technique was used to treat 21 primary pterygia;mitomycin C was used to treat 20 (16 primary, 4 recurrent) pterygia;18 (17 primary, 1 recurrent) pterygia were treated by conjuntival flap reconstruction;and 18 (9 primary, 9 recurrent) pterygia were treated by conjunctival autografting technique. All patients who underwent surgery were followed up for between 6 months and 2 years.
Eight recurrences (38.09%) were observed in the bare sclera group whereas there were 5 (25%) recurrences in the mitomycin C group. In the conjunctival flap reconstruction group, 6 (33.33%) recurrences were detected. In the conjunctival autografting group, 3 recurrences were observed. There were no major complications threatening visual ability in the surgical patients.
A comparison of the groups demonstrated that the recurrence rate was highest in the bare sclera group, and lowest in conjunctival autografting and mitomycin C treatment groups respectively. Although the conjunctival autografting technique is a more difficult and time consuming technique than the others, cosmetic and surgical results were found to be superior. We advise conjunctival autografting for the treatment of pterygium in view of the high recurrence rates of other techniques, and the possible complications of mitomycin C treatment for benign disease.
比较翼状胬肉手术的各种技术,包括单纯巩膜术、术中应用丝裂霉素C、结膜瓣重建术和结膜自体移植术。
本研究旨在比较4种目前使用的技术,以确定翼状胬肉切除术后的并发症和复发率。研究纳入了60例患者的77只眼。单纯巩膜术用于治疗21例原发性翼状胬肉;丝裂霉素C用于治疗20例(16例原发性,4例复发性)翼状胬肉;18例(17例原发性,1例复发性)翼状胬肉采用结膜瓣重建术治疗;18例(9例原发性,9例复发性)翼状胬肉采用结膜自体移植术治疗。所有接受手术的患者均随访6个月至2年。
单纯巩膜术组观察到8例复发(38.09%),而丝裂霉素C组有5例复发(25%)。结膜瓣重建术组检测到6例复发(33.33%)。结膜自体移植组观察到3例复发。手术患者中没有严重威胁视力的并发症。
组间比较表明,单纯巩膜术组的复发率最高,结膜自体移植术组和丝裂霉素C治疗组的复发率分别最低。虽然结膜自体移植术比其他技术更困难、耗时更长,但发现其美容和手术效果更好。鉴于其他技术的高复发率以及丝裂霉素C治疗良性疾病可能出现的并发症,我们建议采用结膜自体移植术治疗翼状胬肉。