ICENI Centre, Colchester Hospital University NHS Foundation Trust, Turner Road, Colchester, Essex, CO4 5JL, UK.
World J Surg. 2012 Feb;36(2):415-23. doi: 10.1007/s00268-011-1328-8.
The enhanced recovery program (ERP) aims to reduce the metabolic response to surgery, hastening recovery and shortening hospital stay. Concerns exist regarding morbidity and hospital stay in elderly patients. The present study aimed to compare the outcomes and compliance of elderly patients managed by an ERP protocol with a younger group.
A review was performed of a prospective database of patients undergoing colorectal resection managed under the ERP protocol between 2005 and 2010. Patients were grouped into <80 years and ≥ 80 years, and perioperative data were collated. The postoperative outcomes were compared with the goals set out by the ERP protocol.
A total of 688 patients were included, 558 were <80 years (median: 66 years; range: 17-79 years) and 130 were ≥ 80 years (median: 83 years; range: 80-95 years). Some 96% of operations were planned laparoscopically. Median total length of hospital stay was 6 days (range: 1-108 days) for the <80 year group and 8 days (range: 1-167 days; P 0.363) for the elderly group, with a 30 day readmission rate of 8.6% for the population and no significant differences between groups. The 30 day mortality was 5%, with a significant difference between the two groups (P < 0.0001). Differences in protocol adherence were identified in the discontinuation of intravenous fluids, catheter removal, and early mobilization.
An enhanced recovery program is feasible for colorectal surgery patients ≥ 80 years of age, with similar compliance as the younger group to some aspects of the protocol and an acceptable readmission rate. Attention to improving compliance in the postoperative phase is necessary, particularly in such high-risk patients, as such improvement may reduce the morbidity and mortality.
加速康复方案(ERP)旨在减轻手术引起的代谢反应,促进康复并缩短住院时间。但对于老年患者,人们对其发病率和住院时间仍存在担忧。本研究旨在比较接受 ERP 方案治疗的老年患者与年轻患者的治疗效果和依从性。
对 2005 年至 2010 年间接受结直肠切除术且采用 ERP 方案治疗的患者前瞻性数据库进行了回顾性分析。将患者分为<80 岁和≥80 岁两组,并收集围手术期数据。将术后结果与 ERP 方案设定的目标进行比较。
共纳入 688 例患者,其中 558 例<80 岁(中位数:66 岁;范围:17-79 岁),130 例≥80 岁(中位数:83 岁;范围:80-95 岁)。96%的手术计划为腹腔镜手术。<80 岁组的中位总住院时间为 6 天(范围:1-108 天),而≥80 岁组为 8 天(范围:1-167 天;P=0.363),两组患者的 30 天再入院率为 8.6%,差异无统计学意义。总体 30 天死亡率为 5%,两组间差异有统计学意义(P<0.0001)。在停止静脉补液、导管拔除和早期活动方面,方案的依从性存在差异。
ERP 方案适用于≥80 岁的结直肠手术患者,在方案的某些方面与年轻患者具有相似的依从性,且再入院率可接受。需要注意的是,在术后阶段提高依从性尤为重要,特别是对这些高风险患者,因为这种改善可能会降低发病率和死亡率。