Martin Thomas D, Lorenz Talya, Ferraro Jane, Chagin Kevin, Lampman Richard M, Emery Karen L, Zurkan Joan E, Boyd Jami L, Montgomery Karin, Lang Rachel E, Vandewarker James F, Cleary Robert K
Division of Colorectal Surgery, Department of Surgery, Saint Joseph Mercy Health System, 5325 Elliott Dr MHVI #104, Ann Arbor, MI, 48106, USA.
Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, USA.
Surg Endosc. 2016 Sep;30(9):4019-28. doi: 10.1007/s00464-015-4714-8. Epub 2015 Dec 22.
Enhanced recovery pathways (ERPs) are thought to improve surgical outcomes by standardizing perioperative patient care established in evidence-based literature. The objective of this study was to determine the impact of a colorectal surgery ERP on hospital length of stay (LOS) and other patient outcomes.
This is a comparative effectiveness study of patients undergoing elective colorectal surgery 2 years prior (pre-ERP group) and 2 years after (ERP group) implementation of an ERP program. The primary outcome was hospital LOS. Secondary outcomes included postoperative complications, 30-day readmissions, and 30-day reoperations. Multivariable regression analyses were utilized to control for patient factors, general health factors, diagnosis, surgeon, colon versus rectal operations, and open versus minimally invasive operations-laparoscopic and robotic. An ERP checklist was developed to track adherence to components of the pathway.
The study population included 1036 patients: 523 in the pre-ERP group and 513 in the ERP group. Unadjusted LOS was significantly shorter in the ERP group than the control pre-ERP group [3 (IQR 3.5) vs 5 days (IQR 4.6); p < 0.0001]. Multivariable regression analysis confirmed the reduction in LOS, controlling for age, colon/rectum procedure, open/laparoscopic/robotic approach, primary diagnosis, and alvimopan use. Postoperative outcomes were not significantly different between groups except for 30-day readmissions, which were unexpectedly higher in the ERP group (14.6 vs 8.7 %, p = 0.04).
A newly implemented ERP on a dedicated colorectal surgery service in an academic non-university hospital setting resulted in shorter hospital LOS, but increased readmissions, for patients undergoing elective open and minimally invasive colon and rectal surgery. Future multi-institutional studies are needed to understand the impact of ERP on postoperative complications and readmissions.
强化康复路径(ERPs)被认为可通过规范基于循证文献确立的围手术期患者护理来改善手术效果。本研究的目的是确定结直肠手术ERP对住院时间(LOS)及其他患者预后的影响。
这是一项对择期结直肠手术患者进行的比较有效性研究,将实施ERP计划前2年的患者(ERP前组)与实施后2年的患者(ERP组)进行对比。主要结局是住院LOS。次要结局包括术后并发症、30天再入院率和30天再次手术率。采用多变量回归分析来控制患者因素、一般健康因素、诊断、外科医生、结肠与直肠手术、开放手术与微创(腹腔镜和机器人)手术。制定了一份ERP检查表以跟踪对路径各组成部分的依从性。
研究人群包括1036例患者:ERP前组523例,ERP组513例。ERP组未经调整的LOS显著短于ERP前对照组[3天(四分位间距3.5)对5天(四分位间距4.6);p<0.0001]。多变量回归分析证实了LOS的缩短,同时控制了年龄、结肠/直肠手术、开放/腹腔镜/机器人手术方式、主要诊断和阿片哌酮的使用。除30天再入院率外,两组术后结局无显著差异,ERP组的30天再入院率意外更高(14.6%对8.7%,p=0.04)。
在一所非大学附属医院的专门结直肠手术科室新实施的ERP,使择期开放和微创结肠及直肠手术患者住院LOS缩短,但再入院率增加。未来需要多机构研究来了解ERP对术后并发症和再入院率的影响。