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社区型医疗机构服务网络内的血压控制差异:探索性分析。

Disparities in blood pressure control within a community-based provider network: an exploratory analysis.

机构信息

Clinical Outcomes Research, Clinical Integration, Sutter Health Support Services, San Francisco, CA, USA.

出版信息

Ann Pharmacother. 2011 Dec;45(12):1473-82. doi: 10.1345/aph.1Q523. Epub 2011 Dec 6.

Abstract

BACKGROUND

Despite treatment for hypertension, blood pressure (BP) remains uncontrolled in many individuals. Identification of patterns in BP control may inform strategies to improve treatment and optimize health outcomes.

OBJECTIVE

To examine patterns in BP control among individuals receiving antihypertensive treatment in a diverse, community-based provider network.

METHODS

In this retrospective exploratory analysis, a total of 51,772 hypertensive subjects were identified in the electronic medical record between January 1, 2007, and June 30, 2010, who were aged 18 years or older, with 2 or more claims for antihypertensive medication, documented race/ethnicity, and 1 or more documented BP readings.

RESULTS

On the basis of Joint National Committee VII guidelines, 76.4% of nondiabetic patients had their BP controlled with treatment (<140/90 mm Hg) and 52.3% of those with diabetes had their BP controlled with treatment (<130/80 mm Hg). The overall rate of BP control was 71.4%. Factors associated with controlled BP included younger age, lower disease burden, better medication adherence, fewer concurrent prescriptions, lower prescription copayments, and living in a region with a higher median household income. Furthermore, when adjusting for age, sex, and disease burden, black (OR 0.68; 95% CI 0.62 to 0.75; p < 0.001), Hispanic (OR 0.80; 95% CI 0.74 to 0.86; p < 0.001), and other race/ethnic group (OR 0.81; 95% CI 0.70 to 0.94; p = 0.005) individuals were less likely than white individuals to have their treated BP controlled. Among nondiabetic hypertensive subjects with controlled BP, the most frequently prescribed therapy was a β-blocker or an angiotensin-converting enzyme (ACE) inhibitor across race/ethnicities; however, those who were black were most frequently prescribed a diuretic or calcium channel blocker. Among diabetic patients with controlled BP, the most frequently prescribed therapy was an ACE inhibitor, regardless of race/ethnicity.

CONCLUSIONS

Potential disparities, particularly among diabetic individuals and those of minority race/ethnicity, were found with regard to BP control and the agents used to treat hypertension. Future studies should address these disparities by designing interventions to improve the treatment of hypertension in high-risk populations.

摘要

背景

尽管接受了高血压治疗,但许多患者的血压(BP)仍然得不到控制。识别血压控制模式可以为改善治疗和优化健康结果提供策略。

目的

在一个多样化的社区医疗服务提供者网络中,研究接受抗高血压治疗的个体中血压控制的模式。

方法

在这项回顾性探索性分析中,在 2007 年 1 月 1 日至 2010 年 6 月 30 日期间,电子病历中确定了 51772 名年龄在 18 岁或以上的高血压患者,他们有 2 次或以上抗高血压药物治疗记录,记录了种族/民族,并且有 1 次或以上记录的血压读数。

结果

根据第七次联合国家委员会指南,76.4%的非糖尿病患者的血压(<140/90 mmHg)得到控制,52.3%的糖尿病患者的血压(<130/80 mmHg)得到控制。总体血压控制率为 71.4%。与血压控制相关的因素包括年龄较小、疾病负担较低、更好的药物依从性、更少的同时处方、更低的处方共付额以及居住在中位数家庭收入较高的地区。此外,当调整年龄、性别和疾病负担时,黑人(OR 0.68;95%CI 0.62 至 0.75;p<0.001)、西班牙裔(OR 0.80;95%CI 0.74 至 0.86;p<0.001)和其他种族/民族(OR 0.81;95%CI 0.70 至 0.94;p=0.005)个体与白人个体相比,血压控制治疗的可能性较小。在血压控制的非糖尿病高血压患者中,β受体阻滞剂或血管紧张素转换酶(ACE)抑制剂是最常开的治疗药物,在不同种族/民族中都是如此;然而,黑人患者最常开的是利尿剂或钙通道阻滞剂。在血压控制的糖尿病患者中,无论种族/民族如何,最常开的治疗药物都是 ACE 抑制剂。

结论

在血压控制和用于治疗高血压的药物方面,发现了潜在的差异,特别是在糖尿病患者和少数民族中。未来的研究应通过设计干预措施来改善高危人群的高血压治疗,以解决这些差异。

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