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晚年抑郁症状:一项国际研究。

Late-life depressive symptoms: an international study.

机构信息

Department of Family Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242-1097, USA.

出版信息

Fam Pract. 2012 Aug;29(4):407-15. doi: 10.1093/fampra/cmr116. Epub 2011 Dec 6.

DOI:10.1093/fampra/cmr116
PMID:22147242
Abstract

OBJECTIVES

Evaluate differences in depressive symptoms, compare sociodemographic and health-related variables associated with depressive symptoms and report level of impact of depressive symptoms on daily activities.

METHODS

Cross-sectional study using a self-administered questionnaire and Patient Health Questionnaire-9 (PHQ-9) diagnostic survey on 1115 patients aged 60-93 years who attended a primary care clinic in Korea, Russia or USA.

RESULTS

At least mild depression (PHQ-9 score of ≥ 5) occurred in 28% of Koreans, 65% of Russian and 27% of US participants. Russians scored more depressed on all PHQ-9 items (P < 0.01) and more suicidal thoughts (P < 0.001), while Koreans had less feelings of worthlessness (P < 0.001). Depression predictors included poorer self-rated health [odds ratio (OR) 2.47, 95% confidence interval (CI) 1.84-3.33, P < 0.0001], chronic diseases (OR 1.34, CI 1.21-1.48, P < 0.0001), female gender (OR 1.56, CI 1.15-2.12, P = 0.0046) and religious attendance (OR 0.88, CI 0.79-0.97, P = 0.0099) for all subjects. Being employed was protective in Korea (OR 0.41, CI 0.21-0.77, P = 0.0061) and being married (OR 0.42, CI 0.27-0.66, P = 0.0002) and of older age (OR 0.95, CI 0.93-0.98, P = 0.0006) protective in US participants. Vascular disease was associated with depressive symptoms in Russia (OR 3.47, CI 1.23-9.80, P = 0.0187). In regression analyses stratified by country for a given level of depressive symptoms, the Russian sample had less impact on daily activities (Russia R (2) = 0.107 versus Korea R (2) = 0.211 and US R (2) = 0.419) P = 0.029.

CONCLUSIONS

Depressive symptoms were more common in Russia than in Korea and USA but had less impact on daily functioning. Cultural or environmental factors may account for this finding.

摘要

目的

评估抑郁症状的差异,比较与抑郁症状相关的社会人口学和健康相关变量,并报告抑郁症状对日常活动的影响程度。

方法

使用自我管理问卷和患者健康问卷-9(PHQ-9)对韩国、俄罗斯或美国的 1115 名年龄在 60-93 岁之间的患者进行横断面研究。

结果

韩国、俄罗斯和美国参与者中分别有 28%、65%和 27%至少有轻度抑郁(PHQ-9 评分≥5)。俄罗斯人在所有 PHQ-9 项目上得分更高(均 P<0.01),自杀想法更多(均 P<0.001),而韩国人则感觉更没有价值(均 P<0.001)。抑郁预测因素包括自评健康状况较差(比值比 2.47,95%置信区间 1.84-3.33,P<0.0001)、慢性疾病(比值比 1.34,CI 1.21-1.48,P<0.0001)、女性(比值比 1.56,CI 1.15-2.12,P=0.0046)和参加宗教活动(比值比 0.88,CI 0.79-0.97,P=0.0099)。对所有受试者而言,在职是保护性的(韩国比值比 0.41,CI 0.21-0.77,P=0.0061),已婚(韩国比值比 0.42,CI 0.27-0.66,P=0.0002)和年龄较大(美国比值比 0.95,CI 0.93-0.98,P=0.0006)是保护性的。在俄罗斯,血管疾病与抑郁症状相关(比值比 3.47,CI 1.23-9.80,P=0.0187)。在按国家分层的回归分析中,对于给定程度的抑郁症状,俄罗斯样本对日常活动的影响较小(俄罗斯 R²=0.107,韩国 R²=0.211,美国 R²=0.419,P=0.029)。

结论

与美国和韩国相比,俄罗斯的抑郁症状更为常见,但对日常功能的影响较小。文化或环境因素可能解释了这一发现。

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