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用于亲水作用电色谱/色谱和免疫亲和色谱的有机整体柱。

Organic monoliths for hydrophilic interaction electrochromatography/chromatography and immunoaffinity chromatography.

机构信息

Department of Chemistry, Oklahoma State University, Stillwater, OK, USA.

出版信息

Electrophoresis. 2012 Jan;33(1):251-61. doi: 10.1002/elps.201100523. Epub 2011 Dec 7.

Abstract

This article is aimed at providing a review of the progress made over the past decade in the preparation of polar monoliths for hydrophilic interaction LC (HILIC)/capillary electrochromatography (HI-CEC) and in the design of immuno-monoliths for immunoaffinity chromatography that are based on some of the polar monolith precursors used in HILIC/HI-CEC. In addition, this review article discusses some of the applications of polar monoliths by HILIC and HI-CEC, and the applications of immuno-monoliths. This article is by no means an exhaustive review of the literature; it is rather a survey of the recent progress made in the field with 83 references published in the past decade on the topics of HILIC and immunoaffinity chromatography monoliths.

摘要

本文旨在综述过去十年中在用于亲水相互作用液相色谱(HILIC)/毛细管电色谱(HI-CEC)的制备的极性整体柱和基于用于 HILIC/HI-CEC 的一些极性整体柱前体的免疫亲和色谱用免疫整体柱的制备方面取得的进展。此外,本文还讨论了 HILIC 和 HI-CEC 中使用的极性整体柱的一些应用以及免疫整体柱的应用。本文绝非对文献的详尽综述,而是对过去十年中在 HILIC 和免疫亲和色谱整体柱主题方面发表的 83 篇文献的综述,概述了该领域的最新进展。

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