Division of Neonatology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, California, USA.
Am J Perinatol. 2012 Apr;29(4):295-300. doi: 10.1055/s-0031-1295636. Epub 2011 Dec 6.
Previous work has shown that fetal hydrographic magnetic resonance imaging (MRI) provided additional information complementary to T2-weighted single-shot fast spin echo (ssFSE) images. The objective of this study was to determine if hydrographic MRI provides better conspicuity of fetal eye structures compared with ssFSE MRI. ssFSE and hydrographic images were retrospectively examined in 82 consecutive fetal studies with normal central nervous system without sensitivity encoding. Relative signal intensity values on ssFSE and hydrographic MRI were obtained for vitreous and sclera. Ratios of the signal intensity of vitreous to the signal intensity of sclera were calculated to determine conspicuity. Similar measurements were obtained in a smaller separate data set (n = 41) using hydrographic imaging with sensitivity encoding techniques. The hydrographic images significantly demonstrated greater conspicuity (ratio of vitreous to sclera) than ssFSE images. This was consistent for both sensitivity encoding and no-sensitivity encoding groups. The difference in conspicuity was on average approximately two times greater in the hydrographic images compared with ssFSE images. Hydrographic MRI of the fetal eye provides on average two times greater conspicuity of fetal eye structures than ssFSE imaging. This enhancement is not affected by gestational age or the use of sensitivity encoding parallel imaging techniques.
先前的工作表明,胎儿水成像磁共振成像(MRI)提供了与 T2 加权单次快速自旋回波(ssFSE)图像互补的额外信息。本研究的目的是确定水成像 MRI 是否比 ssFSE MRI 更能显示胎儿眼部结构。对 82 例连续的正常中枢神经系统胎儿研究进行了回顾性 ssFSE 和水成像检查,未使用敏感度编码。在 ssFSE 和水成像 MRI 上获得了玻璃体和巩膜的相对信号强度值。计算玻璃体信号强度与巩膜信号强度的比值,以确定可见度。使用带有敏感度编码技术的水成像在较小的独立数据集(n=41)中获得了类似的测量值。水成像图像显著显示出比 ssFSE 图像更高的可见度(玻璃体与巩膜的比值)。对于敏感度编码和无敏感度编码组都是如此。与 ssFSE 图像相比,水成像图像的可见度差异平均约大两倍。胎儿眼部水成像 MRI 比 ssFSE 成像平均能提高两倍的胎儿眼部结构可见度。这种增强不受胎龄或使用敏感度编码并行成像技术的影响。