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Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery.

作者信息

Melancon Bruce J, Hopkins Corey R, Wood Michael R, Emmitte Kyle A, Niswender Colleen M, Christopoulos Arthur, Conn P Jeffrey, Lindsley Craig W

机构信息

Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.

出版信息

J Med Chem. 2012 Feb 23;55(4):1445-64. doi: 10.1021/jm201139r. Epub 2012 Jan 6.

DOI:10.1021/jm201139r
PMID:22148748
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3349997/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/9ad9edd244e5/nihms345458f11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/c33776884684/nihms345458f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/5d1034a20e65/nihms345458f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/9dc38b28c2ce/nihms345458f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/3306a4ac077f/nihms345458f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/0e602142488a/nihms345458f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/53dfc8dd865f/nihms345458f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/5052decd0cfa/nihms345458f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/65f77bd7dba2/nihms345458f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/89b87f2d26fb/nihms345458f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/3c38b0036ac2/nihms345458f10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/9ad9edd244e5/nihms345458f11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/c33776884684/nihms345458f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/5d1034a20e65/nihms345458f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/9dc38b28c2ce/nihms345458f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/3306a4ac077f/nihms345458f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/0e602142488a/nihms345458f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/53dfc8dd865f/nihms345458f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/5052decd0cfa/nihms345458f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/65f77bd7dba2/nihms345458f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/89b87f2d26fb/nihms345458f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/3c38b0036ac2/nihms345458f10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/3349997/9ad9edd244e5/nihms345458f11.jpg

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