Department of Ophthalmology, Van State Hospital, Van, Turkey.
J Ocul Pharmacol Ther. 2012 Apr;28(2):205-7. doi: 10.1089/jop.2011.0161. Epub 2011 Dec 8.
The aim of this article is to create awareness among medical colleagues regarding the severe ophthalmic side effects associated with topiramate use.
A case of severe acute bilateral angle closure glaucoma with visual blurring after oral topiramate therapy.
This case was successfully managed by discontinuing topiramate and by starting anti-glaucoma medication. Intraocular pressure, acute transient myopia, and anterior chamber depth were normalized.
It is important for clinicians to recognize these conditions and educate patients about these serious adverse effects when prescribing topiramate.
本文旨在使医学同仁了解托吡酯相关的严重眼部副作用。
托吡酯口服治疗后出现严重急性双侧闭角型青光眼伴视力模糊 1 例。
停用托吡酯并开始使用抗青光眼药物后,该病例得到成功治疗。眼内压、急性短暂性近视和前房深度恢复正常。
临床医生在开具托吡酯时,识别这些情况并教育患者这些严重不良反应非常重要。