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新诊断出 HIV 感染患者住院的原因和感知到的医疗可及性:对 HIV 检测项目的启示。

Causes of hospitalization and perceived access to care among persons newly diagnosed with HIV infection: implications for HIV testing programs.

机构信息

University of Texas Health Science Center at Houston School of Public Health, Houston, Texas, USA.

出版信息

AIDS Patient Care STDS. 2012 Feb;26(2):81-6. doi: 10.1089/apc.2011.0040. Epub 2011 Dec 7.

Abstract

There has been little research on the causes of hospitalization when patients are first diagnosed with HIV in the hospital. Reduced access to care could partially explain inpatient diagnosis. We sought to determine if the patients diagnosed as inpatients are hospitalized due to a HIV-related cause versus some other causes, to compare access to care of patients diagnosed with HIV in hospital and outpatient settings, and to determine factors associated with access to care. Participants were newly diagnosed with HIV and recruited between January 2006 and August 2007. The reason for hospitalization was classified as HIV-related, other infectious cause, noninfectious cause, or miscellaneous cause. Access to care was self-reported using a six-item scale and scores were compared with the t test. Multivariate linear regression determined factors associated with improved access to care. Of 185 participants in the study, 78 were diagnosed in hospital and 107 in outpatient settings. Thirty-two percent of participants were female, 90% were racial/ethnic minority, 45% had no high school diploma, and 85% were uninsured. HIV-related conditions accounted for 60% of admissions, followed by non-infectious causes (20%) and other infectious causes (17%). Inpatients did not report less access to care than patients diagnosed while outpatients. Multivariate analysis demonstrated improvement in access to care with better health insurance (p = 0.01) and greater education (p = 0.08). HIV-related preventable conditions account for many hospitalizations when patients are first diagnosed with HIV. While socioeconomic factors are associated with perceived access to care, persons diagnosed in the inpatient setting do not report lower perceived access to care than persons diagnosed as outpatients, suggesting other barriers to earlier diagnosis.

摘要

在医院首次诊断出 HIV 的患者中,关于住院原因的研究甚少。获得医疗服务的机会减少可能部分解释了住院诊断。我们试图确定诊断为住院患者的住院原因是否是 HIV 相关原因,还是其他原因,比较在医院和门诊环境下诊断出 HIV 的患者获得医疗服务的情况,并确定与获得医疗服务相关的因素。参与者是在 2006 年 1 月至 2007 年 8 月期间新诊断出 HIV 的患者,并进行了招募。住院的原因分为 HIV 相关、其他感染性原因、非传染性原因和其他原因。使用六分量表报告获得医疗服务的情况,并通过 t 检验进行比较。多变量线性回归确定与获得医疗服务相关的因素。在 185 名研究参与者中,78 名在医院诊断,107 名在门诊诊断。32%的参与者为女性,90%为少数民族,45%没有高中文凭,85%没有医疗保险。HIV 相关疾病占住院原因的 60%,其次是非传染性疾病(20%)和其他感染性疾病(17%)。与门诊诊断的患者相比,住院患者报告的获得医疗服务的机会并不少。多变量分析表明,医疗保险状况更好(p=0.01)和教育程度更高(p=0.08)与获得医疗服务的机会改善相关。当患者首次被诊断出 HIV 时,与 HIV 相关的可预防疾病会导致许多住院治疗。虽然社会经济因素与获得医疗服务的感知相关,但在住院环境中诊断出的患者与在门诊诊断出的患者相比,并不报告较低的获得医疗服务的感知,这表明存在其他障碍会导致更早的诊断。

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本文引用的文献

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Estimated HIV incidence in the United States, 2006-2009.2006-2009 年美国估计的艾滋病毒发病率。
PLoS One. 2011;6(8):e17502. doi: 10.1371/journal.pone.0017502. Epub 2011 Aug 3.
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Prevention of HIV-1 infection with early antiretroviral therapy.早期抗逆转录病毒疗法预防 HIV-1 感染。
N Engl J Med. 2011 Aug 11;365(6):493-505. doi: 10.1056/NEJMoa1105243. Epub 2011 Jul 18.

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