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一种用于放射治疗中兆伏级能量光子束剂量学的新型水等效 2D 塑料闪烁体探测器阵列。

A new water-equivalent 2D plastic scintillation detectors array for the dosimetry of megavoltage energy photon beams in radiation therapy.

机构信息

Département de Physique, de Génie Physique et d'Optique, Université Laval, Québec, Québec G1K 7P4, Canada.

出版信息

Med Phys. 2011 Dec;38(12):6763-74. doi: 10.1118/1.3664007.

Abstract

PURPOSE

The objective of this work is to present a new 2D plastic scintillation detectors array (2D-PSDA) designed for the dosimetry of megavoltage (MV) energy photon beams in radiation therapy and to characterize its basic performance.

METHODS

We developed a 2D detector array consisting of 781 plastic scintillation detectors (PSDs) inserted into a plane of a water-equivalent phantom. The PSDs were distributed on a 26 × 26 cm(2) grid, with an interdetector spacing of 10 mm, except for two perpendicular lines centered on the detection plane, where the spacing was 5 mm. Each PSD was made of a 1 mm diameter by 3 mm long cylindrical polystyrene scintillating fiber coupled to a clear nonscintillating plastic optical fiber. All of the light signals emitted by the PSDs were read simultaneously with an optical system at a rate of one measurement per second. We characterized the performance of the optical system, the angular dependency of the device, and the perturbation of dose distributions caused by the hundreds of PSDs inserted into the phantom. We also evaluated the capacity of the system to monitor complex multileaf collimator (MLC) sequences such as those encountered in step-and-shoot intensity modulated radiation therapy (IMRT) plans. We compared our results with calculations performed by a treatment planning system and with measurements taken with a 2D ionization chamber array and with a radiochromic film.

RESULTS

The detector array that we developed allowed us to measure doses with an average precision of better than 1% for cumulated doses equal to or greater than 6.3 cGy. Our results showed that the dose distributions produced by the 6-MV photon beam are not perturbed (within ±1.1%) by the presence of the hundreds of PSDs located into the phantom. The results also showed that the variations in the beam incidences have little effect on the dose response of the device. For all incidences tested, the passing rates of the gamma tests between the 2D-PSDA and the treatment planning system were higher than 97.5% when the standard clinical tolerances of 3% or 3 mm were used. Excellent agreement was obtained between the doses measured and calculated when we used the 2D-PSDA for monitoring a MLC sequence from a step-and-shoot IMRT plan.

CONCLUSIONS

We demonstrated the feasibility of using a large number of PSDs in a new 2D-PSDA for the dosimetry of MV energy photon beams in radiation therapy. The excellent precision, accuracy, and low angular dependence of the device indicate that such a prototype could potentially be used as a high-accuracy quality assurance tool for IMRT and arc therapy patient plan verification. The homogeneity and water-equivalence of the prototype we built suggest that this technology could be extended to multiple detection planes by arranging the fibers into more complex orientations, opening the possibility for 3D dosimetry with PSDs.

摘要

目的

本研究旨在介绍一种新的二维塑料闪烁体探测器阵列(2D-PSDA),用于放射治疗中兆伏(MV)能量光子束的剂量测定,并对其基本性能进行特征描述。

方法

我们开发了一种由 781 个插入水等效体模平面的塑料闪烁体探测器(PSD)组成的二维探测器阵列。PSD 分布在 26×26cm²的网格上,探测器之间的间距为 10mm,除了检测平面中心的两条垂直线上,间距为 5mm。每个 PSD 由一根直径为 1mm、长 3mm 的圆柱形聚苯乙烯闪烁纤维与一根透明的无闪烁塑料光纤耦合而成。所有的 PSD 发出的光信号都通过一个光学系统以每秒一次的速度同时进行读取。我们对光学系统的性能、设备的角度依赖性以及在体模中插入数百个 PSD 引起的剂量分布的干扰进行了特征描述。我们还评估了系统监测复杂多叶准直器(MLC)序列的能力,例如在步进和调强放射治疗(IMRT)计划中遇到的序列。我们将我们的结果与治疗计划系统的计算结果进行了比较,并与二维电离室阵列和光致变色胶片的测量结果进行了比较。

结果

我们开发的探测器阵列允许我们在累积剂量等于或大于 6.3cGy 时,以平均精度优于 1%的水平测量剂量。我们的结果表明,6MV 光子束产生的剂量分布不受位于体模中的数百个 PSD 的干扰(在±1.1%以内)。结果还表明,光束入射角的变化对设备的剂量响应影响很小。对于所有测试的入射角,当使用 3%或 3mm 的标准临床容限时,2D-PSDA 和治疗计划系统之间的伽马测试通过率均高于 97.5%。当使用 2D-PSDA 监测步进和调强 IMRT 计划的 MLC 序列时,我们获得了剂量测量值和计算值之间的良好一致性。

结论

我们证明了在新的二维 PSDA 中使用大量 PSDS 进行放射治疗中 MV 能量光子束剂量测定的可行性。该设备具有出色的精度、准确性和低角度依赖性,表明这种原型可以潜在地用作 IMRT 和弧形治疗患者计划验证的高精度质量保证工具。我们构建的原型的均匀性和水等效性表明,通过将纤维排列成更复杂的方向,可以将该技术扩展到多个检测平面,从而有可能使用 PSDS 进行 3D 剂量测定。

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