Alexander B M, Van Kirk E A, Murdoch W J
Department of Animal Science, University of Wyoming, Laramie 82071.
Life Sci. 1990;47(10):865-8. doi: 10.1016/0024-3205(90)90599-m.
Secretion of platelet-activating factor (PAF) in vitro by ovine follicles and ovarian interstitium obtained at various times before, during and after the endogenous preovulatory surge of luteinizing hormone (LH) and ovulation was quantified by radioimmunoassay. Release of PAF by the preovulatory follicle increased within 2 h after initiation of the surge of LH. Capacity for secretion of PAF was greatest at the time of ovulation, then declined thereafter. Production of PAF by ovarian interstitium throughout the periovulatory period was relatively low and did not change with time. It appears that PAF could act as an intrafollicular mediator in the mechanisms of ovulation and(or) luteinization.
通过放射免疫测定法对在促黄体生成素（LH）内源性排卵前激增及排卵之前、期间和之后的不同时间获取的绵羊卵泡和卵巢间质体外分泌血小板活化因子（PAF）的情况进行了定量分析。排卵前卵泡释放的PAF在LH激增开始后2小时内增加。PAF的分泌能力在排卵时最强，之后便下降。在整个围排卵期，卵巢间质产生的PAF相对较少，且不随时间变化。PAF似乎可能在排卵和（或）黄体化机制中作为卵泡内介质发挥作用。
