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颈动脉支架置入术,无需后扩张。

Carotid artery stenting without post-dilation.

机构信息

Department of Cardiology, CardioVascular Center, University Hospital Motol, 2nd Medical School, Charles University, Prague, Czech Republic.

出版信息

J Interv Cardiol. 2012 Apr;25(2):190-6. doi: 10.1111/j.1540-8183.2011.00694.x. Epub 2011 Dec 8.

DOI:10.1111/j.1540-8183.2011.00694.x
PMID:22150803
Abstract

INTRODUCTION

The aim of this study is to report the feasibility, safety, and 1-year restenosis rate of carotid artery stenting (CAS) without post-dilation.

METHODS

Between April 2006 and November 2009, 254 consecutive patients (68.7 ± 8.5 years old, 31% symptomatic) underwent 308 CAS procedures with the intention of avoiding post-dilation (eligibility criteria were stenosis of less than 30% after stent placement with no overt signs of calcification). Comparison and analysis of mid-term clinical outcomes and restenosis rates of CAS with or without post-dilation was performed retrospectively.

RESULTS

Overall, 27 patients (study group) were eligible for treatment without post-dilation. No significant difference in adverse events was found between the study and control group. In the study group, 2 transient ischemic attacks (7.4%) occurred immediately after the procedure and no other neurological complications were reported during the 30-day, 6-month, and 1-year follow-ups (3 patients died from causes unrelated to the procedure). Two asymptomatic restenosis cases were diagnosed in the study group within the first 12-months after the procedure compared to 16 significant restenosis cases diagnosed in the control group (7.4% vs 5.7%, NS). All of them were successfully treated with repeated intervention.

CONCLUSION

We suggest that CAS without post-dilation is feasible and probably safe with a low rate of cerebrovascular events and restenosis in a selected group of patients. We also suggest that CAS with postdeployment stenosis of less than 20% and without overt signs of severe calcification might be performed without post-dilation.

摘要

介绍

本研究旨在报告颈动脉支架置入术(CAS)不后扩张的可行性、安全性和 1 年再狭窄率。

方法

2006 年 4 月至 2009 年 11 月,254 例连续患者(68.7±8.5 岁,31%有症状)接受了 308 例 CAS 手术,目的是避免后扩张(入选标准为支架置入后狭窄小于 30%,无明显钙化迹象)。回顾性比较和分析有无后扩张的 CAS 的中期临床结果和再狭窄率。

结果

总体而言,27 例患者(研究组)符合无后扩张治疗的条件。研究组和对照组的不良事件发生率无显著差异。在研究组中,2 例短暂性脑缺血发作(7.4%)在手术后立即发生,在 30 天、6 个月和 1 年的随访期间无其他神经并发症(3 例患者死于与手术无关的原因)。研究组在手术后 12 个月内诊断出 2 例无症状再狭窄病例,而对照组诊断出 16 例显著再狭窄病例(7.4%比 5.7%,无显著性差异)。所有患者均通过重复介入治疗成功治疗。

结论

我们建议在选择的患者群体中,CAS 不后扩张是可行的,可能是安全的,且脑血管事件和再狭窄的发生率较低。我们还建议 CAS 后扩张狭窄小于 20%,无明显严重钙化迹象,可能无需后扩张。

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