Anatomy Institute, Lisbon Faculty of Medicine, Lisbon, Portugal; Department of Neuroradiology, Santa Maria Hospital, Lisbon, Portugal; and Department of Neurosurgery, Santa Maria Hospital, Lisbon, Portugal.
Neuromodulation. 2008 Jan;11(1):13-22. doi: 10.1111/j.1525-1403.2007.00138.x.
Objectives. Identification, delimitation, and stereotactic localization of the human nucleus accumbens (Acc) in order to allow its accurate definition and three-dimensional targeting on magnetic resonance imaging (MRI) enabling its use for deep brain stimulation. Methods. Magnetic resonance imaging and anatomical coronal serial cuts were performed on 24 Acc from human cadaver brains perpendicular to the anterior commissure-posterior commissure line; identification, localization, and determination of its dimensions and three-dimensional stereotactic coordinates. Results. Twenty Acc were studied anatomically, 14 by MRI and 12 by both methods. The contours of the Acc were traced and the dimensions measured; mean values: length 10.5 mm, width 14.5 mm and height 7.0 mm. The stereotactic coordinates were obtained every millimeter along its length. Conclusion. It was possible to identify well the human Acc, define its limits and establish its three-dimensional coordinates as potential MRI-guided stereotactic target.
在人体大脑中识别、界定和进行立体定位伏隔核（Acc），以便在磁共振成像（MRI）上对其进行准确定义和三维靶向，从而将其用于脑深部刺激。方法：对 24 个人体大脑尸检标本进行磁共振成像和冠状面连续切片，与前连合-后连合线垂直；识别、定位、确定其维度和三维立体定向坐标。结果：20 个 Acc 通过解剖学研究，14 个通过 MRI 研究，12 个通过两种方法研究。Acc 的轮廓被追踪并测量了其尺寸；平均值：长度 10.5 毫米，宽度 14.5 毫米，高度 7.0 毫米。沿着其长度每毫米获得了立体定向坐标。结论：可以很好地识别人类 Acc，界定其范围，并建立其三维坐标，作为潜在的 MRI 引导的立体定向靶点。
