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动机访谈和互动技能训练对父母改变近期发病精神分裂症青年使用大麻的影响:一项随机对照试验。

Motivational interviewing and interaction skills training for parents to change cannabis use in young adults with recent-onset schizophrenia: a randomized controlled trial.

机构信息

Department of Psychiatry, Academic Medical Centre, Amsterdam, The Netherlands.

出版信息

Psychol Med. 2012 Aug;42(8):1627-36. doi: 10.1017/S0033291711002832. Epub 2011 Dec 8.

DOI:10.1017/S0033291711002832
PMID:22152121
Abstract

BACKGROUND

Cannabis use by people with schizophrenia has been found to be associated with family distress and poor clinical outcomes. Interventions to reduce drug use in this patient group have had limited efficacy. This study evaluated the effectiveness of a novel intervention for parents of young adults with recent-onset schizophrenia consisting of family-based motivational interviewing and interaction skills (Family Motivational Intervention, FMI) in comparison with routine family support (RFS).

METHOD

In a trial with 75 patients who used cannabis and received treatment for recent-onset schizophrenia, 97 parents were randomly assigned to either FMI (n=53) or RFS (n=44). Assessments were conducted at baseline and 3 months after completion of the family intervention by an investigator who remained blind throughout the study about the assignment of the parents.

RESULTS

At follow-up, patients' frequency and quantity of cannabis use was significantly more reduced in FMI than in RFS (p<0.05 and p<0.04 respectively). Patients' craving for cannabis was also significantly reduced in FMI whereas there was a small increase in RFS (p=0.01). There was no difference between FMI and RFS with regard to patients' other substance use and general level of functioning. Both groups showed significant improvements in parental distress and sense of burden.

CONCLUSIONS

Training parents in motivational interviewing and interaction skills is feasible and effective in reducing cannabis use among young adults with recent-onset schizophrenia. However, FMI was not more effective than RFS in increasing patients' general level of functioning and in reducing parents' stress and sense of burden.

摘要

背景

研究发现,精神分裂症患者使用大麻与家庭困扰和临床结局不佳有关。针对该患者群体减少药物使用的干预措施效果有限。本研究评估了一种针对近期发病的精神分裂症青年患者的父母的新型干预措施(基于家庭的动机访谈和互动技能,即家庭动机干预,FMI)的有效性,该措施与常规家庭支持(RFS)进行比较。

方法

在一项针对 75 名使用大麻且接受近期发病精神分裂症治疗的患者的试验中,97 名父母被随机分配到 FMI 组(n=53)或 RFS 组(n=44)。在研究期间,研究者对所有参与者进行了评估,评估在基线时和家庭干预完成后 3 个月进行,研究者对父母的分配情况保持盲态。

结果

在随访时,FMI 组患者的大麻使用频率和数量明显低于 RFS 组(分别为 p<0.05 和 p<0.04)。FMI 组患者对大麻的渴望也明显减少,而 RFS 组则略有增加(p=0.01)。FMI 和 RFS 组在患者的其他物质使用和一般功能水平方面没有差异。两组的父母困扰和负担感均有显著改善。

结论

对父母进行动机访谈和互动技能培训在减少近期发病的精神分裂症青年患者的大麻使用方面是可行且有效的。然而,FMI 并没有比 RFS 更有效地提高患者的一般功能水平,也没有减轻父母的压力和负担感。

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