Vaney Neelam, Anjana Yumnam, Khaliq Farah
Department of Physiology, University of Medical Sciences, Delhi, India.
Funct Neurol. 2011 Jul-Sep;26(3):159-63.
Attention deficit hyperactivity disorder (ADHD) is a neurobehavioral developmental disorder characterized by lack of sustained attention and hyperactivity. It has been suggested that asymmetrical conduction of the auditory stimulus in the brainstem plays a role in the pathophysiological process of ADHD. In the present study, the functional integrity of the central auditory pathway was assessed using the auditory brainstem response (ABR), mid-latency response (MLR) and slow vertex response (SVR). Twenty ADHD children and twenty controls were recruited for the study and recordings were done on a computerized evoked potential recorder using the 10-20 system of electrode placement. There emerged no significant difference in absolute peak latencies, interpeak latencies and amplitude of ABR or latency of MLR in the ADHD children as compared with the controls. Prolongation of the SVR latency was found in the children with ADHD versus the controls, but the difference was statistically insignificant. The present study does not suggest any auditory conduction abnormality as a contributory factor in ADHD.
注意力缺陷多动障碍（ADHD）是一种神经行为发育障碍，其特征为缺乏持续注意力和多动。有人提出，脑干中听觉刺激的不对称传导在ADHD的病理生理过程中起作用。在本研究中，使用听觉脑干反应（ABR）、中潜伏期反应（MLR）和慢顶点反应（SVR）评估了中枢听觉通路的功能完整性。招募了20名ADHD儿童和20名对照进行研究，并使用10-20电极放置系统在计算机化诱发电位记录仪上进行记录。与对照组相比，ADHD儿童的ABR绝对峰潜伏期、峰间潜伏期和振幅或MLR潜伏期没有显著差异。与对照组相比，ADHD儿童的SVR潜伏期延长，但差异无统计学意义。本研究未表明任何听觉传导异常是ADHD的一个促成因素。
