线粒体-内质网连接：功能单元的遗传。
Mitochondrial-ER tethering: the inheritance of a functional unit.
机构信息
Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, 3801 University Ave, Rm 660, Montreal, Quebec H3A 2B4, Canada.
出版信息
Curr Biol. 2011 Dec 6;21(23):R949-51. doi: 10.1016/j.cub.2011.10.043. Epub 2011 Dec 5.
PMID:22153161
Abstract
A new study uncovers a novel role for the endoplasmic reticulum in tethering mitochondria specifically at the tip of the growing bud in Saccharomyces cerevisiae. Mitochondrial anchoring to the bud tip requires the tethering factor Mmr1, and the link to the ER is coupled to the cell cycle through a phosphorylation-dependent mechanism.
摘要
一项新的研究揭示了内质网在将线粒体特异性地锚定在酿酒酵母生长芽尖端的新作用。线粒体锚定到芽尖端需要连接因子 Mmr1，并且与内质网的连接通过依赖于磷酸化的机制与细胞周期偶联。
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