Bababeygy Simon R, Almarzouki Hashem, Buffenn Angela N
Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
J AAPOS. 2011 Dec;15(6):587-9. doi: 10.1016/j.jaapos.2011.06.010.
Lemierre syndrome is characterized by pharyngotonsillitis that is typically secondary to Fusobacterium necrophorum infection and causes adjacent septic thrombophlebitis and thrombosis with subsequent metastatic abscesses. A 3-year-old boy presented with fever, tonsillar enlargement, and bilateral otomastoiditis with purulent discharge. Physical examination revealed abducens nerve palsy on the left side, with a compensatory left head turn. Otomastoid discharge culture was positive for anaerobic F. necrophorum. Magnetic resonance venography of the head and neck revealed thromboses in left internal jugular vein, left cavernous sinus, left superior ophthalmic vein, and left sigmoid sinus. The patient was treated with anticoagulation and a 10-week course of intravenous antibiotics, including ceftriaxone and metronidazole.
勒米尔综合征的特征是咽炎扁桃体炎,通常继发于坏死梭杆菌感染,可导致相邻部位的化脓性血栓性静脉炎和血栓形成,随后出现转移性脓肿。一名3岁男孩出现发热、扁桃体肿大以及双侧耳乳突炎伴脓性分泌物。体格检查发现左侧外展神经麻痹,伴有代偿性左侧头部转动。耳乳突分泌物培养显示厌氧坏死梭杆菌阳性。头颈部磁共振静脉造影显示左侧颈内静脉、左侧海绵窦、左侧眼上静脉和左侧乙状窦血栓形成。该患者接受了抗凝治疗以及为期10周的静脉抗生素治疗,包括头孢曲松和甲硝唑。