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[人类大脑发育过程中神经节隆起和纹状体血管网络的体视学分析]

[Stereological analysis of the vascular network of the ganglionic eminence and the corpus striatum during brain development in man].

作者信息

Marinković R, Marković L

机构信息

Medicinski fakultet, Novi Sad, Zavod za anatomiju.

出版信息

Med Pregl. 1990;43(1-2):13-5.

PMID:2215384
Abstract

A study of the volume density of the ganglionic eminence vascular network and the constituent parts of the corpus striatum was performed on 8 chosen foetal brains, which were well-injected with a mixture of India ink and gelatin, aged from 14-25 postovulatory weeks. The volume density of the ganglionic eminence vascular network amounts to 0.0209-0.0300 mm0, of the caudate nucleus to 0.0131-0.0181 mm0, of the putamen to 0.0136-0.0159 mm0, and of the globus pallidus to 0.0121-0.0159 mm0. The comparison of the results obtained, shows that the volume density of the ganglionic eminence vascular network is higher than the volume density of the other examined structures and that this difference is statistically highly significant (p less than 0.01). The augmented volume density of the ganglionic eminence vascular network points to a possibility of slow blood flow through its vascular bed, which was experimentally demonstrated on animals. This slow blood flow, among other factors, may be the cause of a ganglionic eminence venous infarction in premature newborns of low birthweight.

摘要

对8个选定的胎儿大脑进行了神经节隆起血管网络和纹状体组成部分的体积密度研究,这些胎儿大脑用印度墨水和明胶的混合物良好注射,排卵后年龄为14 - 25周。神经节隆起血管网络的体积密度为0.0209 - 0.0300mm0,尾状核为0.0131 - 0.0181mm0,壳核为0.0136 - 0.0159mm0,苍白球为0.0121 - 0.0159mm0。对所得结果的比较表明,神经节隆起血管网络的体积密度高于其他检查结构的体积密度,且这种差异在统计学上具有高度显著性(p小于0.01)。神经节隆起血管网络体积密度的增加表明其血管床可能存在血流缓慢的情况,这在动物实验中得到了证实。这种血流缓慢,在其他因素中,可能是低出生体重早产儿神经节隆起静脉梗死的原因。

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