[Doyne's honeycomb choroiditis].

This paper describes the retinal changes of 11 parents whose children had the typical clinical manifestation of Doyne's honeycomb choroiditis. In 7 cases, the nonexudative ("dry") form of senile macular degeneration was discovered, 3 of these had increased number of drusen, and 4 of them were with large and confluent drusen, often with scattered pigmentation. Three parents had the exudative-hemorrhagic form, and 1 parent had a cicatricial form of senile macular degeneration. Since Doyne's honeycomb choroiditis is transmitted with the autosomal dominant trait of inheritance, it is indirectly established that Doyne's honeycomb choroiditis progresses into one form of senile macular degeneration, and that senile macular degeneration is partly genetically determined.