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与泰国曼谷注射吸毒者接受美沙酮治疗相关的因素。

Factors associated with methadone treatment among injection drug users in Bangkok, Thailand.

机构信息

Urban Health Research Initiative, British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, 608 - 1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6.

出版信息

J Subst Abuse Treat. 2012 Jul;43(1):108-13. doi: 10.1016/j.jsat.2011.10.022. Epub 2011 Dec 5.

Abstract

Little is known about the characteristics of injection drug users (IDU) who take methadone treatment in Thailand. We examined prevalence and correlates of methadone treatment among a community-recruited sample of IDU in Bangkok, Thailand. Among 273 participants, 143 (52.4%) reported accessing methadone treatment within the previous 6 months. Older age (adjusted odds ratio [AOR] = 1.90, 95% confidence interval [CI] = 1.10-3.30) and more than weekly midazolam injection (AOR = 1.85, 95% CI = 1.04-3.29) were positively associated, whereas alcohol use (AOR = 0.34, 95% CI = 0.18-0.63) and noninjection methamphetamine use (AOR = 0.49, 95% CI = 0.29-0.85) were negatively associated with methadone treatment. In subanalyses, 98.6% of IDU on methadone continued to inject drugs, and the most common reason for stopping methadone was becoming incarcerated (49%). Evidence-based addiction treatment in the form of methadone maintenance therapy, with attention paid to concomitant midazolam injection in this setting, should be implemented.

摘要

关于在泰国接受美沙酮治疗的注射吸毒者(IDU)的特征,人们知之甚少。我们检查了在曼谷招募的 IDU 社区样本中,美沙酮治疗的流行率和相关因素。在 273 名参与者中,有 143 名(52.4%)报告在过去 6 个月内接受过美沙酮治疗。年龄较大(调整后的优势比 [AOR] = 1.90,95%置信区间 [CI] = 1.10-3.30)和每周注射咪达唑仑超过一次(AOR = 1.85,95% CI = 1.04-3.29)与美沙酮治疗呈正相关,而饮酒(AOR = 0.34,95% CI = 0.18-0.63)和非注射性甲基苯丙胺使用(AOR = 0.49,95% CI = 0.29-0.85)与美沙酮治疗呈负相关。在亚分析中,98.6%接受美沙酮治疗的 IDU 继续注射毒品,停止美沙酮治疗的最常见原因是被监禁(49%)。应实施以美沙酮维持治疗为形式的基于证据的成瘾治疗,并注意在此环境下同时注射咪达唑仑。

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