Urban Health Research Initiative, British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, 608 - 1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6.
J Subst Abuse Treat. 2012 Jul;43(1):108-13. doi: 10.1016/j.jsat.2011.10.022. Epub 2011 Dec 5.
Little is known about the characteristics of injection drug users (IDU) who take methadone treatment in Thailand. We examined prevalence and correlates of methadone treatment among a community-recruited sample of IDU in Bangkok, Thailand. Among 273 participants, 143 (52.4%) reported accessing methadone treatment within the previous 6 months. Older age (adjusted odds ratio [AOR] = 1.90, 95% confidence interval [CI] = 1.10-3.30) and more than weekly midazolam injection (AOR = 1.85, 95% CI = 1.04-3.29) were positively associated, whereas alcohol use (AOR = 0.34, 95% CI = 0.18-0.63) and noninjection methamphetamine use (AOR = 0.49, 95% CI = 0.29-0.85) were negatively associated with methadone treatment. In subanalyses, 98.6% of IDU on methadone continued to inject drugs, and the most common reason for stopping methadone was becoming incarcerated (49%). Evidence-based addiction treatment in the form of methadone maintenance therapy, with attention paid to concomitant midazolam injection in this setting, should be implemented.
关于在泰国接受美沙酮治疗的注射吸毒者(IDU)的特征,人们知之甚少。我们检查了在曼谷招募的 IDU 社区样本中,美沙酮治疗的流行率和相关因素。在 273 名参与者中,有 143 名(52.4%)报告在过去 6 个月内接受过美沙酮治疗。年龄较大(调整后的优势比 [AOR] = 1.90,95%置信区间 [CI] = 1.10-3.30)和每周注射咪达唑仑超过一次(AOR = 1.85,95% CI = 1.04-3.29)与美沙酮治疗呈正相关,而饮酒(AOR = 0.34,95% CI = 0.18-0.63)和非注射性甲基苯丙胺使用(AOR = 0.49,95% CI = 0.29-0.85)与美沙酮治疗呈负相关。在亚分析中,98.6%接受美沙酮治疗的 IDU 继续注射毒品,停止美沙酮治疗的最常见原因是被监禁(49%)。应实施以美沙酮维持治疗为形式的基于证据的成瘾治疗,并注意在此环境下同时注射咪达唑仑。