Department of Neurology, Monash Medical School, Alfred Hospital, Melbourne, Victoria, Australia.
J Clin Neurosci. 2012 Jan;19(1):158-61. doi: 10.1016/j.jocn.2011.07.020. Epub 2011 Dec 7.
We report two patients with biopsy-proven audiovestibular sarcoidosis who presented with hearing loss, vertigo and gait ataxia. Oto-neurological investigations confirmed the presence of sensorineural hearing loss, vestibular hypofunction and abnormal auditory brainstem responses. MRI scans of the brain revealed enhancement of the vestibulo-cochlear nerves. Both patients responded to high dose oral corticosteroid treatment, although one patient has required multiple trials of immunosuppressant drug therapy because of relapsing disease.
我们报告了两例经活检证实的听觉前庭结节病患者，他们表现为听力损失、眩晕和步态共济失调。耳神经学检查证实存在感音神经性听力损失、前庭功能低下和听觉脑干反应异常。脑部 MRI 扫描显示前庭耳蜗神经增强。两名患者均对大剂量口服皮质类固醇治疗有反应，但其中一名患者因疾病复发需要多次免疫抑制药物治疗。
