Department of Plastic and Reconstructive Surgery, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
J Plast Reconstr Aesthet Surg. 2012 May;65(5):564-71. doi: 10.1016/j.bjps.2011.09.027. Epub 2011 Dec 11.
Desmoid fibromatosis (also known as infantile or aggressive fibromatosis) is a rare soft tissue tumour that is occasionally seen in children. Although histologically benign, its growth pattern is highly aggressive often showing invasion of surrounding musculature and bone. Frequently found in cosmetically sensitive areas, complete excision can present a challenging problem. However, incomplete surgical excision is associated with high recurrence rates and although the disease responds to chemo and radiotherapy, both carry significant risks in young children. The management of four paediatric desmoid fibromatoses occurring in the midface is discussed. The recent and pertinent literature is comprehensively reviewed and an algorithm for the management of paediatric desmoid fibromatoses is proposed.
硬纤维瘤病（也称为婴儿型或侵袭性纤维瘤病）是一种罕见的软组织肿瘤，偶见于儿童。尽管组织学上为良性，但它的生长方式极具侵袭性，常表现为周围肌肉和骨骼的浸润。硬纤维瘤病常发生于美容敏感区域，完全切除可能会带来挑战。然而，不完全手术切除与高复发率相关，尽管该疾病对化疗和放疗有反应，但在幼儿中这两种治疗方法都存在重大风险。本文讨论了发生于面中部的 4 例儿童硬纤维瘤病的治疗。本文全面回顾了近期相关文献，并提出了儿童硬纤维瘤病的治疗方案。
