Pierce I T, Gatehouse P D, Kalodiki E, Lattimer C, Geroulakos G, Xu X Y, Firmin D N
Royal Brompton Hospital Trust, UK.
Phlebology. 2012 Oct;27(7):352-9. doi: 10.1258/phleb.2011.011053. Epub 2011 Dec 8.
Assessment and optimization of intermittent pneumatic compression (IPC) devices for prophylaxis of deep vein thrombosis has previously used duplex ultrasound. The aim was to investigate novel magnetic resonance (MR) venous velocity mapping (VM) for IPC research and development.
Twelve normal subjects were scanned in the supine position using realtime MR VM with sequential foot and calf IPC (120 mmHg) at 1.5 T. Measurements were taken in the popliteal vein at baseline using both cuffs and each cuff individually recording 60 seconds continuously. Temporal resolution was 310 ms per independent image, at 1 × 1 mm spatial resolution.
Peak velocity (V(p)) measurements: baseline, V(p) = 2.1 cm/second (range = 1.1-3.5); using both compression cuffs, V(p) = 41.5 cm/second (18.0-58.1); calf cuff alone, V(p) = 40.6 cm/second (18.1-62.2); foot cuff alone, V(p) = 7.9 cm/second (4.2-15.3). Flow volume measurements per compression cycle (F): baseline, F = 2.3 cm³ (0.5-11.4); both compression cuffs, F = 7.1 cm³ (2.5-24.6); calf cuff only, F = 7.1 cm³ (2.4-24.5); foot cuff only, F = 2.6 cm³ (0.9-10.7). The foot cuff contribution was insignificant when combined with the calf cuff (P < 0.01). The MR venous VM results were similar to those reported elsewhere using ultrasound.
This novel technique for MR venous VM can measure the realtime variations in venous blood flow during IPC.
先前对用于预防深静脉血栓形成的间歇性气动压迫（IPC）装置的评估和优化采用了双功超声。本研究旨在探讨用于IPC研发的新型磁共振（MR）静脉血流速度成像（VM）技术。
12名正常受试者仰卧位接受扫描，在1.5T磁场下采用实时MR VM技术，对足部和小腿依次进行IPC（120mmHg）。使用双袖带及每个袖带单独对腘静脉进行测量，每次连续记录60秒。独立图像的时间分辨率为310毫秒，空间分辨率为1×1毫米。
峰值流速（V(p)）测量结果：基线时，V(p)=2.1厘米/秒（范围=1.1 - 3.5）；使用双袖带时，V(p)=41.5厘米/秒（18.0 - 58.1）；仅使用小腿袖带时，V(p)=40.6厘米/秒（18.1 - 62.2）；仅使用足部袖带时，V(p)=7.9厘米/秒（4.2 - 15.3）。每个压迫周期的血流量（F）测量结果：基线时，F = 2.3立方厘米（0.5 - 11.4）；使用双袖带时，F = 7.1立方厘米（2.5 - 24.6）；仅使用小腿袖带时，F = 7.1立方厘米（2.4 - 24.5）；仅使用足部袖带时，F = 2.6立方厘米（0.9 - 10.7）。当与小腿袖带联合使用时，足部袖带的作用不显著（P < 0.01）。MR静脉VM结果与其他地方使用超声报告的结果相似。
这种用于MR静脉VM的新技术能够测量IPC期间静脉血流的实时变化。
