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2011 年原发性醛固酮增多症:对病因和后果认识的进一步提高。

Primary aldosteronism in 2011: Towards a better understanding of causation and consequences.

机构信息

Endocrine Hypertension Research Center, University of Queensland School of Medicine, Greenslopes and Princess Alexandra Hospitals, Ipswich Road, Woolloongabba, Brisbane 4102, Australia.

出版信息

Nat Rev Endocrinol. 2011 Dec 13;8(2):70-2. doi: 10.1038/nrendo.2011.223.

Abstract

With primary aldosteronism now widely acknowledged as common and associated with both hypertension-related and non-hypertension-related pathology, research interest into its causes and consequences continues to grow. In 2011, major breakthroughs occurred in understanding the role and nature of underlying genetic disturbances and elucidating the pathophysiology of its cardiovascular sequelae.

摘要

随着原发性醛固酮增多症(primary aldosteronism)被广泛认为是一种常见病症,与高血压相关和非高血压相关的病理都有关联,对其病因和后果的研究兴趣持续增长。2011 年,在理解潜在遗传紊乱的作用和性质以及阐明其心血管后果的病理生理学方面取得了重大突破。

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