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早期体外生命支持用于韦格纳肉芽肿伴弥漫性肺泡出血和急性呼吸窘迫综合征的救治:一例报告及文献复习

Early extracorporeal life support as rescue for Wegener granulomatosis with diffuse alveolar hemorrhage and acute respiratory distress syndrome: a case report and literature review.

作者信息

Joseph Mark, Charles Anthony G

机构信息

Division of Trauma and Critical Care Surgery, Department of Surgery, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599-7228, USA.

出版信息

Pediatr Emerg Care. 2011 Dec;27(12):1163-6. doi: 10.1097/PEC.0b013e31823b01a2.

Abstract

OBJECTIVE

The study's objective was to report a case and review the literature on the use of extracorporeal life support in the face of severe pulmonary hemorrhage for acute respiratory distress syndrome.

STUDY SELECTION

This study is a single case report of a pediatric patient who was successfully managed on venovenous extracorporeal life support for severe acute respiratory distress syndrome with acute pulmonary hemorrhage secondary to Wegener disease.

CONCLUSIONS

Extracorporeal life support can be used successfully in selected patients with respiratory failure with pulmonary hemorrhage. The cautious use of anticoagulation should be balanced with the risk of bleeding, mindful of the need for other measures to mitigate severe bleeding if this should occur.

摘要

目的

本研究的目的是报告一例病例,并回顾有关在严重肺出血情况下使用体外生命支持治疗急性呼吸窘迫综合征的文献。

研究选择

本研究是一例儿科患者的单病例报告,该患者因韦格纳肉芽肿病继发严重急性呼吸窘迫综合征伴急性肺出血,通过静脉-静脉体外生命支持成功治疗。

结论

体外生命支持可成功用于某些伴有肺出血的呼吸衰竭患者。谨慎使用抗凝治疗时应权衡出血风险,同时要考虑到如果发生严重出血需采取其他措施来减轻出血。

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