Loforte Antonio, Lilla Della Monica Paola, Montalto Andrea, Musumeci Francesco
Dipartimento di cardiochirurgia e Trapianti di Cuore, Ospedale San Camillo, Roma.
G Ital Cardiol (Rome). 2011 Dec;12(12):839-45. doi: 10.1714/996.10830.
When patients at high risk for failure of isolated left ventricular assist device (LVAD) support are identified, biventricular assist device implantation is suggested as a primary option. Results of a planned temporary right ventricular mechanical support (RVAD) placement in high-risk LVAD recipients have been reported and analyzed.
Between 2009 and 2011, 10 consecutive adult patients (9 men; age range 31-69 years), with preoperative evidence of moderate to severe biventricular failure, were supported simultaneously with an axial flow HeartMate II (Thoratec Corp., Pleasanton, California) LVAD and a temporary CentriMag (Levitronix LCC, Waltham, Massachusetts) RVAD as a primary option at our institution. Indications for support at implantation were ischemic dilated cardiomyopathy in 6 cases and idiopathic dilated cardiomyopathy in 4. Planned temporary RVAD insertion was defined as RVAD support placement at the same time as LVAD placement.
Nine patients were successfully weaned from temporary RVAD support after an average time of 18.6 days (range 3-43 days) and discharged from hospital. One patient died due to respiratory failure. RVAD removal was performed through a minimally invasive approach without repeat sternotomy in 6 patients. None of the patients required a permanent RVAD support.
When patients at high risk for failure of isolated LVAD support are identified, temporary biventricular assist device implantation is advised to improve the outcome of such a vulnerable patient population.
当确定孤立性左心室辅助装置(LVAD)支持失败风险较高的患者时,建议将双心室辅助装置植入作为主要选择。已有关于高危LVAD接受者计划性临时右心室机械支持(RVAD)置入的结果报告及分析。
2009年至2011年期间,在我们机构,10例连续的成年患者(9例男性;年龄范围31 - 69岁),术前有中度至重度双心室衰竭证据,作为主要选择同时接受轴流HeartMate II(Thoratec公司,加利福尼亚州普莱森顿)LVAD和临时CentriMag(Levitronix LCC,马萨诸塞州沃尔瑟姆)RVAD支持。植入时的支持指征为6例缺血性扩张型心肌病和4例特发性扩张型心肌病。计划性临时RVAD置入定义为与LVAD置入同时进行RVAD支持放置。
9例患者在平均18.6天(范围3 - 43天)后成功撤离临时RVAD支持并出院。1例患者因呼吸衰竭死亡。6例患者通过微创方法移除RVAD,无需再次开胸。所有患者均无需永久性RVAD支持。
当确定孤立性LVAD支持失败风险较高的患者时,建议植入临时双心室辅助装置以改善这类脆弱患者群体的预后。