Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.
Nat Rev Nephrol. 2011 Dec 13;8(2):66-8. doi: 10.1038/nrneph.2011.196.
Understanding the complex interactions between the various pathways disrupted in polycystic kidney and liver disease is essential to identify and optimize therapies for these disorders. Studies published in the past year have demonstrated a functional interaction between the main proteins implicated in these diseases and identified novel therapeutic approaches.
了解多囊肾病和肝病中各种途径紊乱的复杂相互作用对于确定和优化这些疾病的治疗方法至关重要。过去一年发表的研究表明,这些疾病中主要涉及的蛋白质之间存在功能相互作用,并确定了新的治疗方法。