Sebe A, Ohshima T, Ebisudani D, Oka H, Matsumoto K, Yoshizima S
Department of Neurosurgery, University of Tokushima.
No Shinkei Geka. 1990 Aug;18(8):761-5.
A 41-year-old male was admitted to our service with right occipital pain as his chief complaint. CT and MRI examinations revealed bilateral chronic subdural hematomas. The patient had also been affected with ITP since the age of 28. Since emergency operation was thought to be dangerous, he was transferred to Tokushima University Hospital, and treated preoperatively by administration of steroids and a large dose of immunoglobulin. When his platelet count had returned to 146,000/mm3, evacuation of the hematoma through burr holes was performed successfully under local anesthesia. The postoperative course was uneventful. So far as we have been able to find in the literature, only 3 cases of ITP complicated by chronic subdural hematoma have been reported. The characteristic clinical feature of these 4 cases including our own case was noted as the absence of a history of trauma. However, the etiological relationship between ITP and chronic subdural hematoma was controversial. Occurrence of chronic subdural hematoma in patients with ITP and in patients under hemodialyzer treatment is very rare. However, intracerebral hemorrhages are rather common among such patients. So it was suggested that the tendency to bleeding among patients with ITP, and among hemodialyzer patients may contribute little as an etiological factor in the evolution of chronic subdural hematoma.
一名41岁男性因右枕部疼痛为主诉入院。CT和MRI检查显示双侧慢性硬膜下血肿。该患者自28岁起就患有特发性血小板减少性紫癜(ITP)。由于急诊手术被认为具有危险性,他被转至德岛大学医院,并在术前接受了类固醇和大剂量免疫球蛋白治疗。当他的血小板计数恢复至146,000/mm³时,在局部麻醉下成功地通过钻孔引流了血肿。术后过程顺利。就我们在文献中所能查到的,仅有3例ITP合并慢性硬膜下血肿的病例被报道。包括我们自己的病例在内,这4例病例的特征性临床特点是均无外伤史。然而,ITP与慢性硬膜下血肿之间的病因关系存在争议。ITP患者及血液透析患者中发生慢性硬膜下血肿非常罕见。然而,此类患者中脑出血较为常见。因此,有人提出ITP患者及血液透析患者的出血倾向作为慢性硬膜下血肿发生发展的病因因素作用可能不大。