Interventional Radiology Section, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA.
Hematology Am Soc Hematol Educ Program. 2011;2011:156-61. doi: 10.1182/asheducation-2011.1.156.
The post-thrombotic syndrome (PTS) develops in 25%-50% of patients with proximal lower extremity deep vein thrombosis (DVT) despite the use of standard anticoagulant therapy and elastic compression stockings. PTS is a major cause of quality of life impairment in DVT patients and often leads to limiting venous claudication, work disability, and venous ulcers. Endovascular thrombolytic procedures that eliminate venous thrombus, restore venous flow, and show strong potential to prevent PTS are now under study in multicenter randomized clinical trials. In addition, endovascular procedures can be used to treat valvular reflux and venous obstruction and thereby provide symptom improvement to patients with chronic established PTS.
血栓后综合征（PTS）尽管使用标准抗凝治疗和弹性压缩袜，仍会在 25%-50%的近端下肢深静脉血栓形成（DVT）患者中发展。PTS 是 DVT 患者生活质量受损的主要原因，常导致静脉跛行、工作能力丧失和静脉溃疡。现在，多中心随机临床试验正在研究消除静脉血栓、恢复静脉血流并显示出预防 PTS 强大潜力的血管内溶栓治疗。此外，血管内手术可用于治疗瓣膜反流和静脉阻塞，从而为慢性 PTS 患者提供症状改善。
