Department of Neuroradiology, University of Munich, Klinikum Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Cardiovasc Intervent Radiol. 2012 Dec;35(6):1326-31. doi: 10.1007/s00270-011-0317-5. Epub 2011 Dec 9.
Treatment of acute stroke by endovascular mechanical recanalisation (EMR) has shown promising results and continues to be further refined. We evaluated the impact of a temporary stent compared with our results using other mechanical devices.
We analysed clinical and radiological data of all patients who were treated by EMR after intravenous thrombolysis for acute carotid T- and middle-cerebral artery (M1) occlusions at our centre between 2007 and 2011. A comparison was performed between those patients in whom solely the stent-retriever was applied (group S) and those treated with other devices (group C).
We identified 14 patients for group S and 16 patients for group C. Mean age, National Institute of Health Stroke Scale score, and time to treatment were 67.1 years and 16.5 and 4.0 h for group S and 61.1 years and 17.6 and 4.5 h for group C, respectively. Successful recanalisation (thrombolysis in cerebral infarction scores ≥IIb) was achieved in 93% of patients in group S and 56% of patients in group C (P < 0.05). Mean recanalisation times for M1 occlusions were 23 min (group S) and 29 min (group C) and for carotid-T occlusions were 39 min (group S) and 50 min (group C), and 45% of the patients in group S and 33% in group C had a favourable outcome (Modified Rankin Scale score ≤2).
The findings suggest an improvement in recanalisation success by the application of a temporary stent compared with previously used devices. These results are to be confirmed by larger studies.
血管内机械再通(EMR)治疗急性中风的效果令人振奋,并在持续改进中。我们评估了临时支架与我们使用其他机械装置的结果相比的影响。
我们分析了 2007 年至 2011 年期间,我们中心在静脉溶栓治疗急性颈内动脉 T 型和大脑中动脉(M1)闭塞后,通过 EMR 治疗的所有患者的临床和影像学数据。对仅使用支架取栓器的患者(S 组)和使用其他器械治疗的患者(C 组)进行了比较。
S 组有 14 例患者,C 组有 16 例患者。S 组患者的平均年龄、国立卫生研究院卒中量表评分和治疗时间分别为 67.1 岁、16.5 分和 4.0 小时,C 组患者的平均年龄、国立卫生研究院卒中量表评分和治疗时间分别为 61.1 岁、17.6 分和 4.5 小时。S 组患者的再通率(血栓溶解脑梗死评分≥Ⅱb)为 93%,C 组患者为 56%(P<0.05)。M1 闭塞的平均再通时间为 S 组 23 分钟,C 组 29 分钟;颈内动脉-T 闭塞的平均再通时间为 S 组 39 分钟,C 组 50 分钟;S 组 45%的患者和 C 组 33%的患者预后良好(改良 Rankin 量表评分≤2)。
与以往使用的器械相比,应用临时支架可提高再通成功率。这些结果有待更大规模的研究证实。