Kaminski P F, Sorosky J I, Mandell M J, Broadstreet R P, Zaino R J
Department of Obstetrics and Gynecology, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey.
Obstet Gynecol. 1990 Nov;76(5 Pt 2):924-6.
Ovarian remnant syndrome results from residual ovarian tissue after bilateral oophorectomy. The syndrome is associated with chronic pelvic pain and is suspected when premenopausal levels of FSH and LH are present in a patient with documented bilateral oophorectomy. Histologic demonstration of ovarian tissue at operation confirms the diagnosis. We treated a patient with ovarian remnant syndrome with a 10-day course of clomiphene citrate, 100 mg daily, to stimulate the residual ovarian tissue and facilitate localization. Preoperative ultrasound revealed a 5.0 x 3.5 x 6.2-cm cystic mass in the right adnexal region. Exploratory laparotomy easily localized the mass, and it was removed intact. Histologic slides demonstrated normal ovarian tissue with multiple follicles in various stages of development and a corpus luteum cyst. Clomiphene citrate is capable of stimulating an ovarian remnant, producing an enlarged, cystic structure easily localized by ultrasound. The increased size and preoperative knowledge of the location facilitated surgical removal.
卵巢残留综合征是双侧卵巢切除术后残留卵巢组织所致。该综合征与慢性盆腔疼痛相关，在已证实双侧卵巢切除的患者中，若出现绝经前水平的促卵泡生成素（FSH）和促黄体生成素（LH），则怀疑患有此综合征。手术中卵巢组织的组织学证实可确诊。我们对一名卵巢残留综合征患者给予枸橼酸氯米芬治疗，疗程为10天，每日100毫克，以刺激残留卵巢组织并便于定位。术前超声检查发现右侧附件区有一个5.0×3.5×6.2厘米的囊性肿物。剖腹探查术很容易就定位了肿物，并完整切除。组织学切片显示为正常卵巢组织，有多个处于不同发育阶段的卵泡及一个黄体囊肿。枸橼酸氯米芬能够刺激卵巢残留组织，产生一个增大的囊性结构，通过超声很容易定位。其增大的体积及术前对位置的了解便于手术切除。
