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腹壁重建中腹膜内疝修补补片的性能比较:动物模型研究

Properties comparison of intraperitoneal hernia meshes in reconstruction of the abdominal wall: animal model study.

作者信息

Ławniczak Piotr, Grobelski Bartłomiej, Pasieka Zbigniew

机构信息

Department of Experimental Surgery, Medical University in Łódź.

出版信息

Pol Przegl Chir. 2011 Jan;83(1):19-26. doi: 10.2478/v10035-011-0003-y.

DOI:10.2478/v10035-011-0003-y
PMID:22166238
Abstract

UNLABELLED

Modern methods of hernia tension free treatment use very wide range of modern biomaterials. Most of them are used transabdominal. For the best and most convenient treatment of large hernias would be a mesh suitable for intraperitoneal use with low adhesion ability to internal organs.THE AIM OF THE STUDY was to compare three types of intraperitoneal meshes. MATERIAL AND METHODS. The study compared three types of intraperitoneal meshes. Sub-chronic (14 days) and chronic (90 days) macro-and microscopic examination were performed on rats (n = 69). Properties of the polypropylene mesh (PLP), Dynamesh®-iPOM and polypropylene covered with chitosan (PLP+chitosan) were evaluated and compared. RESULTS. It has been shown that the test meshes differ slightly during the healing process.

CONCLUSION

The PLP+chitosan mesh had the best biocompatible features of them all.

摘要

未标注

现代无张力疝修补术使用了非常广泛的现代生物材料。其中大多数是经腹使用。对于大型疝的最佳且最方便的治疗方法是一种适用于腹腔内使用且对内脏器官粘附能力低的补片。

本研究的目的是比较三种类型的腹腔内补片。

材料与方法。本研究比较了三种类型的腹腔内补片。对大鼠(n = 69)进行了亚慢性(14天)和慢性(90天)的大体和显微镜检查。评估并比较了聚丙烯补片(PLP)、Dynamesh®-iPOM和壳聚糖覆盖的聚丙烯(PLP+壳聚糖)的特性。

结果。结果表明,在愈合过程中,测试补片略有不同。

结论

PLP+壳聚糖补片在所有补片中具有最佳的生物相容性特征。

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Biomed Res Int. 2015;2015:821279. doi: 10.1155/2015/821279. Epub 2015 Oct 4.
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Effects of chitosan coatings on polypropylene mesh for implantation in a rat abdominal wall model.壳聚糖涂层对聚丙烯网片在大鼠腹壁模型中植入的影响。
Tissue Eng Part A. 2013 Dec;19(23-24):2713-23. doi: 10.1089/ten.TEA.2012.0739. Epub 2013 Aug 21.